The paper presents a comprehensive overview of the use of artificial intelligence (AI)
systems in drug design. Neural networks, which are one of the systems employed in AI, are …

Genotoxicity data are mainly interpreted in a qualitative way, which typically results in a
binary classification of chemical entities. For more than a decade, there has been a …

Commonly consumed foods and beverages can contain chemicals with reported
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …

The “totality” of the human exposure is conceived to encompass life-associated endogenous
and exogenous aggregate exposures. Process-related contaminants (PRCs) are not only …

Exposure to multiple substances is a challenge for risk evaluation. Currently, there is an
ongoing debate if generic “mixture assessment/allocation factors”(MAF) should be …

Globally, industries and regulatory authorities are faced with an urgent need to assess the
potential adverse effects of chemicals more efficiently by embracing new approach …

Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20%
of all lung cancer deaths. Increased risk associated with living near trafficked roads …

Bioactive plant derived compounds are important for a wide range of therapeutic
applications, and some display promising anticancer properties. Further evidence suggests …

Arsenic is widely present in the environment and is associated with various population
health risks including cancers. Arsenic exposure at environmentally relevant levels …

The probiotic Escherichia coli strain Nissle 1917 (DSM 6601, Mutaflor), generally
considered beneficial and safe, has been used for a century to treat various intestinal …