Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

Colorectal cancer (CRC) is the most common cancer of the digestive system with high
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …

Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

Accumulating evidence suggested that both gut microbiome and sex play a critical role in
the efficacy of immune checkpoint blockade therapy. Considering the reciprocal relationship …

Background. Of all intestinal microbiome‐derived metabolites, trimethylamine N‐oxide
(TMAO) has received increasing attention because of its potent role in colorectal cancer …

Periodontitis, an oral inflammatory disease, originates from periodontal microbiota dysbiosis
which is associated with the dysregulation of host immunoinflammatory response. This …

Trimethylamine N-oxide (TMAO) is a microbial metabolite derived from nutrients, such as
choline, L-carnitine, ergothioneine and betaine. Recently, it has come under the spotlight for …

Diet is an important determinant of health and consequently is often implicated in the
development of disease, particularly gastrointestinal (GI) diseases, given the high …

The generation of gut microbiota-derived trimethylamine N-oxide (TMAO) from the
metabolism of dietary L-carnitine and choline is associated with a high risk of major adverse …

Osteoporosis and osteoarthritis account for the leading causes of musculoskeletal
dysfunction in older adults. Senescent chondrocyte overburden, inflammation, oxidative …