Bacterial urease and its role in long-lasting human diseases

I Konieczna, P Zarnowiec, M Kwinkowski… - Current protein and …, 2012 - ingentaconnect.com
Urease is a virulence factor found in various pathogenic bacteria. It is essential in
colonization of a host organism and in maintenance of bacterial cells in tissues. Due to its …

Combinatorial peptide libraries: mining for cell-binding peptides

BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

From combinatorial chemistry to cancer-targeting peptides

OH Aina, R Liu, JL Sutcliffe, J Marik… - Molecular …, 2007 - ACS Publications
Several monoclonal antibodies that target cell surface receptors have gained approval by
the US Food and Drug Administration and are widely used in the treatment of some cancers …

[HTML][HTML] Peptide arrays: development and application

LC Szymczak, HY Kuo, M Mrksich - Analytical chemistry, 2018 - ncbi.nlm.nih.gov
Peptide arrays are an exciting and rapidly growing technology with a broad range of
applications in the basic and applied life sciences. Peptide arrays have been under …

Peptide ligand-modified nanomedicines for targeting cells at the tumor microenvironment

A David - Advanced drug delivery reviews, 2017 - Elsevier
Since their initial discovery more than 30 years ago, tumor-homing peptides have become
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …

Related impurities in peptide medicines

M D'Hondt, N Bracke, L Taevernier, B Gevaert… - … of pharmaceutical and …, 2014 - Elsevier
Peptides are an increasingly important group of pharmaceuticals, positioned between
classic small organic molecules and larger bio-molecules such as proteins. Currently, the …

AntiJen: a quantitative immunology database integrating functional, thermodynamic, kinetic, biophysical, and cellular data

CP Toseland, DJ Clayton, H McSparron… - Immunome …, 2005 - Springer
AntiJen is a database system focused on the integration of kinetic, thermodynamic,
functional, and cellular data within the context of immunology and vaccinology. Compared to …

Recent innovations in peptide based targeted drug delivery to cancer cells

Y Gilad, M Firer, G Gellerman - Biomedicines, 2016 - mdpi.com
Targeted delivery of chemotherapeutics and diagnostic agents conjugated to carrier ligands
has made significant progress in recent years, both in regards to the structural design of the …

[图书][B] Phage display in biotechnology and drug discovery

SS Sidhu, CR Geyer - 2015 - books.google.com
The book provides a comprehensive view of the impact and promise of phage display in
drug discovery and biotechnology. Building on the success of its previous edition, the book …

A novel peptide isolated from a phage display peptide library with trastuzumab can mimic antigen epitope of HER-2

B Jiang, W Liu, H Qu, L Meng, S Song, T Ouyang… - Journal of Biological …, 2005 - ASBMB
Trastuzumab, a humanized antibody to HER-2, has been shown to be effective in the
treatment of breast cancer in which HER-2 overexpression and metastasis occurs. In our …