Bioengineered in vitro models of the kidney offer unprecedented opportunities to better
mimic the in vivo microenvironment. Kidney-on-a-chip technology reproduces 2D or 3D …

Many different strategies can be found in the literature to model organ physiology, tissue
functionality, and disease in vitro; however, most of these models lack the physiological fluid …

Recent advances in the development of microfluidic systems for the culture of complex and
three-dimensional cell, tissue, and organ models allow their use in toxicity studies and …

Liver-related drug metabolism is a key aspect of pharmacokinetics and possible toxicity.
From this perspective, the availability of advanced in vitro models for drug testing is still an …

Here, we report a fluorescent electrospun nanofiber membrane for integration into
microfluidic devices towards lung-on-a-chip applications complemented with the results of …

Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …

In a myriad of developmental and degenerative brain diseases, characteristic pathological
biomarkers are often associated with cerebral blood flow and vasculature. However, the …

Mechanical properties are among the key considerations for the design and fabrication of
complex tissue models and implants. In addition to the choice of material and the processing …

Tumor metastasis involves complex processes that traditional 2D cultures and animal
models struggle to fully replicate. Metastatic tumors undergo a multitude of transformations …

The cell barrier is built to delineate tissue compartments and regulate the substance
exchange between different compartments. In this work, we developed a microfluidic tool for …