The importance of breast adipose tissue in breast cancer
C Kothari, C Diorio, F Durocher - International journal of molecular …, 2020 - mdpi.com
Adipose tissue is a complex endocrine organ, with a role in obesity and cancer. Adipose
tissue is generally linked to excessive body fat, and it is well known that the female breast is …
tissue is generally linked to excessive body fat, and it is well known that the female breast is …
Emerging functions of regulatory T cells in tissue homeostasis
A Sharma, D Rudra - Frontiers in immunology, 2018 - frontiersin.org
CD4+ Foxp3+ regulatory T-cells (Tregs) are a unique subset of helper T-cells, which
regulate immune response and establish peripheral tolerance. Tregs not only maintain the …
regulate immune response and establish peripheral tolerance. Tregs not only maintain the …
Adipokines mediate inflammation and insulin resistance
H Kwon, JE Pessin - Frontiers in endocrinology, 2013 - frontiersin.org
For many years, adipose tissue was considered as an inert energy storage organ that
accumulates and stores triacylglycerols during energy excess and releases fatty acids in …
accumulates and stores triacylglycerols during energy excess and releases fatty acids in …
Adipokines in inflammation and metabolic disease
The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …
Adipose tissue-liver cross talk in the control of whole-body metabolism: implications in nonalcoholic fatty liver disease
V Azzu, M Vacca, S Virtue, M Allison, A Vidal-Puig - Gastroenterology, 2020 - Elsevier
Adipose tissue and the liver play significant roles in the regulation of whole-body energy
homeostasis, but they have not evolved to cope with the continuous, chronic, nutrient …
homeostasis, but they have not evolved to cope with the continuous, chronic, nutrient …
[HTML][HTML] Adipokines: a link between obesity and cardiovascular disease
Obesity is a risk factor for various cardiovascular diseases including hypertension,
atherosclerosis, and myocardial infarction. Recent studies aimed at understanding the …
atherosclerosis, and myocardial infarction. Recent studies aimed at understanding the …
[HTML][HTML] Inflammatory links between obesity and metabolic disease
CN Lumeng, AR Saltiel - The Journal of clinical …, 2011 - Am Soc Clin Investig
The obesity epidemic has forced us to evaluate the role of inflammation in the health
complications of obesity. This has led to a convergence of the fields of immunology and …
complications of obesity. This has led to a convergence of the fields of immunology and …
[HTML][HTML] The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of …
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases
worldwide, as it affects up to 30% of adults in Western countries. Moreover, NAFLD is also …
worldwide, as it affects up to 30% of adults in Western countries. Moreover, NAFLD is also …
Adipose tissue remodeling and obesity
K Sun, CM Kusminski, PE Scherer - The Journal of clinical …, 2011 - Am Soc Clin Investig
To fulfill its role as the major energy-storing tissue, adipose has several unique properties
that cannot be seen in any other organ, including an almost unlimited capacity to expand in …
that cannot be seen in any other organ, including an almost unlimited capacity to expand in …
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
Rapamycin, an inhibitor of mechanistic target of rapamycin complex 1 (mTORC1), extends
the life spans of yeast, flies, and mice. Calorie restriction, which increases life span and …
the life spans of yeast, flies, and mice. Calorie restriction, which increases life span and …