Insulin sensitivity: modulation by nutrients and inflammation
S Schenk, M Saberi, JM Olefsky - The Journal of clinical …, 2008 - Am Soc Clin Investig
Insulin resistance is a major metabolic feature of obesity and is a key factor in the etiology of
a number of diseases, including type 2 diabetes. In this review, we discuss potential …
a number of diseases, including type 2 diabetes. In this review, we discuss potential …
Adiponectin receptor as a key player in healthy longevity and obesity-related diseases
T Yamauchi, T Kadowaki - Cell metabolism, 2013 - cell.com
Adiponectin is a fat-derived hormone whose reduction plays central roles in obesity-linked
diseases including insulin resistance/type 2 diabetes and atherosclerosis. The cloning of …
diseases including insulin resistance/type 2 diabetes and atherosclerosis. The cloning of …
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice
C Postic, J Girard - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity, insulin resistance, and
type 2 diabetes. NAFLD represents a large spectrum of diseases ranging from (i) fatty liver …
type 2 diabetes. NAFLD represents a large spectrum of diseases ranging from (i) fatty liver …
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
We examined mouse models with altered adipocyte expression of mitoNEET, a protein
residing in the mitochondrial outer membrane, to probe its impact on mitochondrial function …
residing in the mitochondrial outer membrane, to probe its impact on mitochondrial function …
[图书][B] Food lipids: chemistry, nutrition, and biotechnology
CC Akoh - 2017 - taylorfrancis.com
Maintaining the high standards that made the previous editions such well-respected and
widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition …
widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition …
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
Dysregulation of lipid metabolism in individual tissues leads to systemic disruption of insulin
action and glucose metabolism. Utilizing quantitative lipidomic analyses and mice deficient …
action and glucose metabolism. Utilizing quantitative lipidomic analyses and mice deficient …
Adipogenesis
K Sarjeant, JM Stephens - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body
insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue …
insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue …
Inflammation as a link between obesity and metabolic syndrome
F Emanuela, M Grazia, DR Marco… - Journal of nutrition …, 2012 - Wiley Online Library
The metabolic syndrome is a complex of clinical features leading to an increased risk for
cardiovascular disease and type 2 diabetes mellitus in both sexes. Visceral obesity and …
cardiovascular disease and type 2 diabetes mellitus in both sexes. Visceral obesity and …
Lipid homeostasis, lipotoxicity and the metabolic syndrome
RH Unger, GO Clark, PE Scherer, L Orci - Biochimica et Biophysica Acta …, 2010 - Elsevier
In the 20th century industrialized nations have become afflicted with an unprecedented
pandemic of increased adiposity. In the United States, the epicenter of the epidemic, over …
pandemic of increased adiposity. In the United States, the epicenter of the epidemic, over …
Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism
KG Kumar, JL Trevaskis, DD Lam, GM Sutton, RA Koza… - Cell metabolism, 2008 - cell.com
Obesity and nutrient homeostasis are linked by mechanisms that are not fully elucidated.
Here we describe a secreted protein, adropin, encoded by a gene, Energy Homeostasis …
Here we describe a secreted protein, adropin, encoded by a gene, Energy Homeostasis …