Migraine is ranked as the second highest cause of disability worldwide and the first among
women aged 15–49 years. Overall, the incidence of migraine is threefold higher among …

In the last two decades, protein–protein interactions (PPIs) have been used as the main
target for drug development. However, with larger or superficial binding sites, it has been …

Stress is an essential adaptive response that enables the organism to cope with challenges
and restore homeostasis. Different stressors require distinctive corrective responses in …

Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …

The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …

Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …

The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …

Objective Sexual activity is a fundamental human function with short-term and long-term
emotional, social, and physical benefits. Yet within healthcare, sexuality has been …

Oxytocin is an important regulator of the social brain. In some animal models of autism,
notably in Magel2 tm1. 1Mus-deficient mice, peripheral administration of oxytocin in infancy …