[HTML][HTML] Intestinal microbiota influences non-intestinal related autoimmune diseases
MC Opazo, EM Ortega-Rocha… - Frontiers in …, 2018 - frontiersin.org
The human body is colonized by millions of microorganisms named microbiota that interact
with our tissues in a cooperative and non-pathogenic manner. These microorganisms are …
with our tissues in a cooperative and non-pathogenic manner. These microorganisms are …
Animal models for diabetes: Understanding the pathogenesis and finding new treatments
A King, J Bowe - Biochemical pharmacology, 2016 - Elsevier
Diabetes mellitus is a lifelong, metabolic disease that is characterised by an inability to
maintain normal glucose homeostasis. There are several different forms of diabetes …
maintain normal glucose homeostasis. There are several different forms of diabetes …
Can exposure to environmental chemicals increase the risk of diabetes type 1 development?
Type 1 diabetes mellitus (T1DM) is an autoimmune disease, where destruction of beta‐cells
causes insulin deficiency. The incidence of T1DM has increased in the last decades and …
causes insulin deficiency. The incidence of T1DM has increased in the last decades and …
Interferon alpha: The key trigger of type 1 diabetes
A Lombardi, E Tsomos, SS Hammerstad… - Journal of autoimmunity, 2018 - Elsevier
IFNα is a cytokine essential to a vast array of immunologic processes. Its induction early in
the innate immune response provides a priming mechanism that orchestrates numerous …
the innate immune response provides a priming mechanism that orchestrates numerous …
Development of the nonobese diabetic mouse and contribution of animal models for understanding type 1 diabetes
Y Mullen - Pancreas, 2017 - journals.lww.com
In 1974, the discovery of a mouse and a rat that spontaneously developed hyperglycemia
led to the development of 2 autoimmune diabetes models: nonobese diabetic (NOD) mouse …
led to the development of 2 autoimmune diabetes models: nonobese diabetic (NOD) mouse …
End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data
A Derr, C Yang, R Zilionis, A Sergushichev… - Genome …, 2016 - genome.cshlp.org
RNA-seq protocols that focus on transcript termini are well suited for applications in which
template quantity is limiting. Here we show that, when applied to end-sequencing data …
template quantity is limiting. Here we show that, when applied to end-sequencing data …
Somatostatin receptor type 2 antagonism improves glucagon counterregulation in biobreeding diabetic rats
N Karimian, T Qin, T Liang, M Osundiji, Y Huang… - Diabetes, 2013 - Am Diabetes Assoc
Impaired counterregulation during hypoglycemia in type 1 diabetes (T1D) is partly
attributable to inadequate glucagon secretion. Intra-islet somatostatin (SST) suppression of …
attributable to inadequate glucagon secretion. Intra-islet somatostatin (SST) suppression of …
Deciphering the pathogenesis of human type 1 diabetes (T1D) by interrogating T cells from the “scene of the crime”
SC Kent, SI Mannering, AW Michels… - Current diabetes reports, 2017 - Springer
Abstract Purpose of Review Autoimmune-mediated destruction of insulin-producing β-cells
within the pancreas results in type 1 diabetes (T1D), which is not yet preventable or curable …
within the pancreas results in type 1 diabetes (T1D), which is not yet preventable or curable …
[HTML][HTML] Prenatal exposure to a mixture of PAHs causes the dysfunction of islet cells in adult male mice: association with type 1 diabetes mellitus
K Ou, J Song, S Zhang, L Fang, L Lin, M Lan… - Ecotoxicology and …, 2022 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) have been detected throughout the human body.
Whether exposure to PAHs is associated with the incidence of type 1 diabetes mellitus …
Whether exposure to PAHs is associated with the incidence of type 1 diabetes mellitus …
Rodent models of diabetic retinopathy as a useful research tool to study neurovascular cross-talk
K Polewik, M Kosek, D Jamrozik, I Matuszek… - Biology, 2023 - mdpi.com
Simple Summary Diabetic retinopathy is a progressive complication of diabetes leading to
vision loss. About one in three diabetic patients has some degree of diabetic retinopathy …
vision loss. About one in three diabetic patients has some degree of diabetic retinopathy …