[PDF][PDF] A pan-cancer single-cell panorama of human natural killer cells

F Tang, J Li, L Qi, D Liu, Y Bo, S Qin, Y Miao, K Yu… - Cell, 2023 - cell.com
Natural killer (NK) cells play indispensable roles in innate immune responses against tumor
progression. To depict their phenotypic and functional diversities in the tumor …

[HTML][HTML] Natural killer cells: a promising immunotherapy for cancer

J Chu, F Gao, M Yan, S Zhao, Z Yan, B Shi… - Journal of translational …, 2022 - Springer
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …

[HTML][HTML] Regulation of placental extravillous trophoblasts by the maternal uterine environment

J Pollheimer, S Vondra, J Baltayeva… - Frontiers in …, 2018 - frontiersin.org
During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

[HTML][HTML] The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity

Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of Clinical Medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …

[HTML][HTML] Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy

L Yang, Z Chu, M Liu, Q Zou, J Li, Q Liu… - Journal of Hematology & …, 2023 - Springer
Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …

[HTML][HTML] Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies

ER Kansler, S Dadi, C Krishna, BG Nixon… - Nature …, 2022 - nature.com
Malignancy can be suppressed by the immune system. However, the classes of
immunosurveillance responses and their mode of tumor sensing remain incompletely …

[PDF][PDF] Dysfunction of natural killer cells by FBP1-induced inhibition of glycolysis during lung cancer progression

J Cong, X Wang, X Zheng, D Wang, B Fu, R Sun… - Cell metabolism, 2018 - cell.com
Natural killer (NK) cells are effector lymphocytes with pivotal roles in the resistance against
various tumors; dysfunction of NK cells often results in advanced tumor progression. Tumors …

[PDF][PDF] Trained memory of human uterine NK cells enhances their function in subsequent pregnancies

M Gamliel, D Goldman-Wohl, B Isaacson, C Gur… - Immunity, 2018 - cell.com
Natural killer cells (NKs) are abundant in the human decidua, regulating trophoblast
invasion and angiogenesis. Several diseases of poor placental development are associated …

The tumor microenvironment in cholangiocarcinoma progression

L Fabris, K Sato, G Alpini, M Strazzabosco - Hepatology, 2021 - Wiley Online Library
Cholangiocarcinoma (CCA) is a malignancy with features of the biliary epithelium. Although
CCA is recognized as a rare cancer, it is the second most common primary liver tumor after …