The role of innate immune cells in the tumor microenvironment and research progress in anti-tumor therapy

C Lu, Y Liu, NM Ali, B Zhang, X Cui - Frontiers in Immunology, 2023 - frontiersin.org
Innate immune cells in the tumor microenvironment (TME) mainly include macrophages,
neutrophils, natural killer cells, dendritic cells and bone marrow derived suppressor cells …

[HTML][HTML] Natural killer cells in the lungs

J Cong, H Wei - Frontiers in immunology, 2019 - frontiersin.org
The lungs, a special site that is frequently challenged by tumors, pathogens and other
environmental insults, are populated by large numbers of innate immune cells. Among …

Natural killer cells in inflammation and autoimmunity

B Zitti, YT Bryceson - Cytokine & Growth Factor Reviews, 2018 - Elsevier
First described 40 years ago, natural killer (NK) cells represent the founding members of the
innate lymphoid cell (ILC) family. They were initially defined by their ability to kill cancer cells …

[HTML][HTML] Obesity-associated alterations of natural killer cells and immunosurveillance of cancer

I Bähr, J Spielmann, D Quandt, H Kielstein - Frontiers in immunology, 2020 - frontiersin.org
Obesity is accompanied by a systemic chronic low-grade inflammation as well as
dysfunctions of several innate and adaptive immune cells. Recent findings emphasize an …

Phase 1 clinical trial of adoptive immunotherapy using “off-the-shelf” activated natural killer cells in patients with refractory and relapsed acute myeloid leukemia

M Boyiadzis, M Agha, RL Redner, A Sehgal, A Im… - Cytotherapy, 2017 - Elsevier
Background aims Activated NK cells (aNK) generated by expansion of a human interleukin-
2–dependent NK cell line (NK-92) were shown to mediate strong anti-leukemia activity. This …

Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria

DO Odera, J Tuju, K Mwai, IN Nkumama… - Science Translational …, 2023 - science.org
Natural killer (NK) cells are potent immune effectors that can be activated via antibody-
mediated Fc receptor engagement. Using multiparameter flow cytometry, we found that NK …

[HTML][HTML] Natural killer cell infiltration is discriminative for antibody-mediated rejection and predicts outcome after kidney transplantation

S Yazdani, J Callemeyn, S Gazut, E Lerut, H de Loor… - Kidney international, 2019 - Elsevier
Despite partial elucidation of the pathophysiology of antibody-mediated rejection (ABMR)
after kidney transplantation, it remains largely unclear which of the involved immune cell …

Tissue-resident NK cells: development, maturation, and clinical relevance

E Hashemi, S Malarkannan - Cancers, 2020 - mdpi.com
Natural killer (NK) cells belong to type 1 innate lymphoid cells (ILC1) and are essential in
killing infected or transformed cells. NK cells mediate their effector functions using non …

Immunological memory cells

W Ratajczak, P Niedźwiedzka-Rystwej… - … European Journal of …, 2018 - termedia.pl
This article reviews immunological memory cells, currently represented by T and B
lymphocytes and natural killer (NK) cells, which determine a rapid and effective response …

[HTML][HTML] On the way to become a natural killer cell

C Di Vito, J Mikulak, D Mavilio - Frontiers in immunology, 2019 - frontiersin.org
Natural Killer (NK) cells are innate lymphocytes playing pivotal roles in host defense and
immune-surveillance. The homeostatic modulation of germ-line encoded/non-rearranged …