Human CD49a+ Lung Natural Killer Cell Cytotoxicity in Response to Influenza A Virus

GE Cooper, K Ostridge, SI Khakoo… - Frontiers in …, 2018 - frontiersin.org
Influenza A virus (IAV) is a major global public health burden due to its routine evasion of
immunization strategies. Natural killer (NK) cells are innate cytotoxic cells with important …

[HTML][HTML] The adverse impact of tumor microenvironment on NK-cell

Z Hu, X Xu, H Wei - Frontiers in Immunology, 2021 - frontiersin.org
NK cells are considered an important component of innate immunity, which is the first line of
defensing against tumors and viral infections in the absence of prior sensitization. NK cells …

High percentages and activity of synovial fluid NK cells present in patients with advanced stage active Rheumatoid Arthritis

R Yamin, O Berhani, H Peleg, S Aamar, N Stein… - Scientific reports, 2019 - nature.com
Rheumatoid Arthritis (RA) causes chronic inflammation of joints. The cytokines TNFα and
IFNγ are central players in RA, however their source has not been fully elucidated. Natural …

[HTML][HTML] NKp44-NKp44 ligand interactions in the regulation of natural killer cells and other innate lymphoid cells in humans

M Parodi, H Favoreel, G Candiano, S Gaggero… - Frontiers in …, 2019 - frontiersin.org
Natural Killer (NK) cells are potent cytotoxic cells belonging to the family of Innate Lymphoid
Cells (ILCs). Their most characterized effector functions are directed to the control of …

Deciphering the killer‐cell immunoglobulin‐like receptor system at super‐resolution for natural killer and T‐cell biology

V Béziat, HG Hilton, PJ Norman, JA Traherne - Immunology, 2017 - Wiley Online Library
Killer‐cell immunoglobulin‐like receptors (KIR s) are components of two fundamental
biological systems essential for human health and survival. First, they contribute to host …

The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56bright NK cells

AE Ziegler, P Fittje, LM Müller, AE Ahrenstorf… - Frontiers in …, 2023 - frontiersin.org
The crosstalk between NK cells and their surrounding environment is enabled through
activating and inhibitory receptors, which tightly control NK cell activity. The co-inhibitory …

Dissecting human ILC heterogeneity: more than just three subsets

Y Simoni, EW Newell - Immunology, 2018 - Wiley Online Library
Innate lymphoid cells (ILC s) have been divided into three distinct groups based on
functional capacities, cytokine profiles and transcription factor expression. Studies …

Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor

S Gaggero, M Bruschi, A Petretto, M Parodi… - …, 2018 - Taylor & Francis
The release of soluble ligands of activating Natural Killer (NK) cell receptors may represent
a regulatory mechanism of NK cell function both in physiologic and in pathologic conditions …

Selenium-containing nanoparticles synergistically enhance Pemetrexed&NK cell-based chemoimmunotherapy

S Pan, T Li, Y Tan, H Xu - Biomaterials, 2022 - Elsevier
NK cell-based immunotherapy and pemetrexed (Pem)-based chemotherapy have broad
application prospects in cancer treatment. However, the over-expressed NK cell inhibitory …

Roles of exosomes as drug delivery systems in cancer immunotherapy: a mini-review

Z Fang, Y Ding, Z Xue, P Li, J Li, F Li - Discover Oncology, 2022 - Springer
Exosomes can be released by a variety of cells and participate in intercellular
communication in many physiological processes in the body. They can be used as carriers …