Mitigation and use of biofilms in space for the benefit of human space exploration

YAV Justiniano, DM Goeres, EL Sandvik, BV Kjellerup… - Biofilm, 2023 - Elsevier
Biofilms are self-organized communities of microorganisms that are encased in an
extracellular polymeric matrix and often found attached to surfaces. Biofilms are widely …

Metagenomic features of bioburden serve as outcome indicators in combat extremity wounds

A Avila-Herrera, JB Thissen, N Mulakken… - Scientific reports, 2022 - nature.com
Battlefield injury management requires specialized care, and wound infection is a frequent
complication. Challenges related to characterizing relevant pathogens further complicates …

Multi-resistant biofilm-forming pathogens on the International Space Station

A Vaishampayan, E Grohmann - Journal of biosciences, 2019 - Springer
Abstract The International Space Station (ISS) is a confined and closed habitat with unique
conditions such as cosmic radiation, and microgravity. These conditions have a strong effect …

Bioaerosols and transmission, a diverse and growing community of practice

S Mubareka, N Groulx, E Savory, T Cutts… - Frontiers in public …, 2019 - frontiersin.org
The transmission of infectious microbes via bioaerosols is of significant concern for both
human and animal health. However, gaps in our understanding of respiratory pathogen …

Mobilizable antibiotic resistance genes are present in dust microbial communities

S Ben Maamar, AJ Glawe, TK Brown, N Hellgeth… - PLoS …, 2020 - journals.plos.org
The decades-long global trend of urbanization has led to a population that spends
increasing amounts of time indoors. Exposure to microbes in buildings, and specifically in …

Sierra Nevada sweep: metagenomic measurements of bioaerosols vertically distributed across the troposphere

C Jaing, J Thissen, M Morrison, MB Dillon… - Scientific reports, 2020 - nature.com
To explore how airborne microbial patterns change with height above the Earth's surface,
we flew NASA's C-20A aircraft on two consecutive days in June 2018 along identical flight …

Draft genome sequences of fungi isolated from the international Space Station during the microbial tracking-2 experiment

AC Simpson, C Urbaniak, JR Bateh… - Microbiology …, 2021 - Am Soc Microbiol
As part of the Microbial Tracking-2 study, 94 fungal strains were isolated from surfaces on
the International Space Station, and whole-genome sequences were assembled …

Microbiology of human spaceflight: microbial responses to mechanical forces that impact health and habitat sustainability

CA Nickerson, RJC McLean, J Barrila… - Microbiology and …, 2024 - journals.asm.org
Understanding the dynamic adaptive plasticity of microorganisms has been advanced by
studying their responses to extreme environments. Spaceflight research platforms provide a …

Challenges and opportunities for bioactive compound and antibiotic discovery in deep space

AC Simpson - Journal of the Indian Institute of Science, 2023 - Springer
Long-term space habitation for exploratory missions or colonization will involve significant
health risks to astronauts living in enclosed habitats in altered gravity, for years at a time with …

Genomic and Functional Characterization of Enterococcus faecalis Isolates Recovered From the International Space Station and Their Potential for Pathogenicity

NC Bryan, F Lebreton, M Gilmore, G Ruvkun… - Frontiers in …, 2021 - frontiersin.org
Enterococcus faecalis is a multidrug resistant, opportunistic human pathogen and a leading
cause of hospital acquired infections. Recently, isolates have been recovered from the air …