A core domain set for pyoderma gangrenosum trial outcomes: an international eDelphi and consensus study from the UPGRADE initiative

ME Jacobson, JW Rick, LAA Gerbens… - British Journal of …, 2024 - academic.oup.com
Background Pyoderma gangrenosum (PG) is a rare ulcerative skin condition with no current
standardized outcomes or outcome measures. With a rich investigational therapeutic …

Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients

M Moelleken, C Erfurt‐Berge, M Ronicke… - International Wound …, 2023 - Wiley Online Library
Pyoderma gangrenosum (PG) is a non‐infectious, neutrophilic dermatosis that was difficult
to diagnose in clinical practice. Today, the PARACELSUS score is a validated tool for …

A novel murine model of pyoderma gangrenosum reveals that inflammatory skin-gut crosstalk is mediated by IL-1β-primed neutrophils

S Jatana, AK Ponti, EE Johnson, NA Rebert… - Frontiers in …, 2023 - frontiersin.org
Pyoderma gangrenosum (PG) is a debilitating skin condition often accompanied by
inflammatory bowel disease (IBD). Strikingly,~ 40% of patients that present with PG have …

[HTML][HTML] Crosstalk between keratinocytes and immune cells in inflammatory skin diseases

X Ni, Y Lai - Exploration of Immunology, 2021 - explorationpub.com
Cutaneous homeostasis is maintained by dynamic cellular communications between
different cell types in the skin through interactions with various mediators, including …

The role of ultra-high-frequency ultrasound in pyoderma gangrenosum: new insights in pathophysiology and diagnosis

G Granieri, A Michelucci, F Manzo Margiotta, B Cei… - Diagnostics, 2023 - mdpi.com
Pyoderma gangrenosum (PG) is a neutrophilic dermatological disease, whose
pathogenesis is still poorly clarified. Because of the lack of validated criteria for diagnosis …

The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” project: a protocol for the development of the core outcome …

J Rick, LJ Gould, AV Marzano, A Garg, D Chen… - Archives of …, 2023 - Springer
Introduction Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that affects
approximately 0.3–6 out of every 100,000 people worldwide. Clinical trials are scarce but …

Positionspapier der Initiative Chronische Wunde (ICW) e. V. zur Nomenklatur des Débridements chronischer Wunden

J Dissemond, A Bültemann, V Gerber, M Motzkus… - Der Hautarzt, 2022 - Springer
Die heute in der Wundbehandlung verwendete Nomenklatur ist interdisziplinär und
interprofessionell sehr unterschiedlich. Daher ist es ein Anliegen der Fachgesellschaft …

Association of all-cause and cause-specific mortality risks with pyoderma gangrenosum

S Lee, JY Lee, HJ Ju, JH Lee, SB Koh, JM Bae… - JAMA …, 2023 - jamanetwork.com
Importance Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis. Few studies
have evaluated the mortality outcomes of patients with PG. Objective To investigate all …

Refractory Takayasu arteritis with recurrent pyoderma gangrenosum: a therapeutic challenge with case-based review

K Bhowmick, R Roongta, S Dey, S Dey, S Mondal… - Clinical …, 2023 - Springer
Takayasu arteritis (TA) is an uncommon chronic granulomatous large-vessel vasculitis
affecting the aorta and its branches. Pyoderma gangrenosum (PG) is a chronic neutrophilic …

Evaluation of neutrophil extracellular trap deregulated formation in pyoderma gangrenosum

C Croia, V Dini, B Loggini, E Manni… - Experimental …, 2021 - Wiley Online Library
Pyoderma gangrenosum (PG) is a neutrophilic dermatose (ND) characterized by a dense
neutrophilic infiltrate in the affected tissue. Neutrophil extracellular traps (NETs) are web‐like …