Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …

There is a paucity of sensitive and specific biomarkers for the early prediction of CKD
progression. The recent application of innovative technologies such as functional genomics …

Interrogation of the human proteome in a highly multiplexed and efficient manner remains a
coveted and challenging goal in biology. We present a new aptamer-based proteomic …

Chronic kidney disease affects millions of people worldwide and is associated with an
increased morbidity and mortality as a result of kidney failure and cardiovascular disease …

While emerging evidence indicates that the incidence of both acute kidney injury (AKI) and
chronic kidney disease (CKD) in children is rising and that the etiologies are dramatically …

Objective Diabetic nephropathy (DN) is characterized by glomerular and tubulointerstitial
injury, proteinuria and remodeling. Here we examined whether the combination of an …

Methods: This follow-up study included n= 85 subjects from the diabetic clinic of Jinnah Post
Graduate Medical Center (JPMC) in collaboration with Aga Khan University from November …

Background: Chronic kidney disease (CKD) is the end point of a number of renal and
systemic diseases. The metabolomics with a highly multiplexed and efficient manner is a …

Background Diabetic nephropathy imposes a substantial cardiovascular and renal burden
contributing to both morbidity and excess mortality. Progression of chronic kidney disease …

Acute kidney injury (AKI) research in the past decade has mostly focused upon development
of a standard AKI definition, validation of early novel biomarkers to predict AKI prior to serum …