Metabolic reprogramming is one of the most important hallmarks of malignant tumors.
Specifically, lipid metabolic reprogramming has marked impacts on cancer progression and …

Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …

Lipid metabolic reprogramming is involved in mediating tamoxifen (TAM) response in breast
cancer cells. Published microarray data indicated that ATP citrate lyase (ACLY) is …

Enhanced de novo lipogenesis mediated by sterol regulatory element–binding proteins
(SREBPs) is thought to be involved in nonalcoholic steatohepatitis (NASH) pathogenesis. In …

Spatially resolved tissue lipidomics is essential for accurate intraoperative and postoperative
cancer diagnosis by revealing molecular information in the tumor microenvironment. Matrix …

The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …

Different studies corroborate a role for ceramide synthases and their downstream products,
ceramides, in modulation of apoptosis and autophagy in the context of cancer. These …

Lipidomics has become an indispensable method for the quantitative assessment of lipid
metabolism in basic, clinical, and pharmaceutical research. It allows for the generation of …

Lipid metabolism reprogramming is an important hallmark of tumor progression. Cancer
cells require high levels of lipid synthesis and uptake not only to support their continued …

Abnormal energy metabolism is a characteristic of tumor cells, and mitochondria are
important components of tumor metabolic reprogramming. Mitochondria have gradually …