Peptide hormones exert unique actions via specific G protein–coupled receptors; however,
the therapeutic potential of regulatory peptides is frequently compromised by rapid …

The worldwide epidemics of obesity and diabetes have been linked to increased sugar
consumption in humans. Here, we review fructose and glucose metabolism, as well as …

Strategies aimed at mimicking or enhancing the action of the incretin hormone glucagon-like
peptide 1 (GLP-1) therapeutically improve glucose-stimulated insulin secretion (GSIS); …

Results: The A1 beta-casein milk led to significantly higher stool consistency values (Bristol
Stool Scale) compared with the A2 beta-casein milk. There was also a significant positive …

OBJECTIVE: Peripheral infusions of glucagon-like peptide-1 (GLP-1) in humans have been
shown to inhibit gastrointestinal motility and decrease hunger and energy intake. However …

The 21st century is characterized by an increasing incidence and prevalence of obesity and
the burden of its associated comorbidities, especially cardiometabolic diseases, which are …

The gastrointestinal tract can assess the nutrient composition of ingested food. The nutrient-
sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the …

Glucagon-like peptide 1 (GLP-1) and GLP-1 analogs have received much recent attention
due to the success of GLP-1 mimetics in treating type II diabetes mellitus (T2DM), but these …

Summary Glucagon-like peptide-1 receptor (GLP-1R) activation within the nucleus tractus
solitarius (NTS) suppresses food intake and body weight (BW), but the intracellular signals …

The aim of the present study was to assess the effect of glucagon-like peptide-1 (GLP-1) on
solid gastric emptying and the subsequent release of pancreatic and intestinal hormones. In …