In 1977, the world witnessed both the eradication of smallpox and the beginning of the
modern age of genomics. Over the following half‐century, 7 epidemic viruses of international …

Quantifying SARS-like coronavirus (SL-CoV) evolution is critical to understanding the origins
of SARS-CoV-2 and the molecular processes that could underlie future epidemic viruses …

In viral evolution, a new mutation has to proliferate within the host (Stage I) in order to be
transmitted and then compete in the host population (Stage II). We now analyze the intrahost …

Learn from the past to predict viral pandemics Skip to main content Thank you for visiting
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ABSTRACT The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic
that emerged in 2019 has been an unprecedented event in international science, as it has …

Objectives Whole-genome sequencing has revolutionised the field of infectious disease
surveillance, enabling near real-time detection of pathogens and tracking how infections …

Viruses display enormous genomic diversity, employing effectively all possible routes for the
expression of genetic information and lacking universally shared genes (1). This diverse …

Your father may have given you your nose, but your sneeze owes its genes to its neighbors.
From family trees to the tree of life, evolution is commonly depicted as an exclusively …

After more than 2 years of intensive investigation, the direct ancestors of the novel severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) remain unidentified. Molecular …

RNA viruses are the primary catalysts for infectious disease outbreaks, epidemics, and
pandemics across multiple hosts including humans. The role of RNA viruses in urban areas …