Advances in quantum dot-based biosensors for DNA-modifying enzymes assay

Q Zhang, X Zhang, F Ma, C Zhang - Coordination Chemistry Reviews, 2022 - Elsevier
DNA-modifying enzymes participate in various genetic functions (eg, DNA replication,
repairing, and recombination) through alternating certain DNA sequence, and the …

Advances in ovarian cancer care and unmet treatment needs for patients with platinum resistance: a narrative review

DL Richardson, RN Eskander, DM O'Malley - JAMA oncology, 2023 - jamanetwork.com
Importance Platinum-based chemotherapy has been the standard of care for ovarian cancer
for the past 3 decades. Although most patients respond to platinum-based treatment …

The impact of vitamin D on cancer: A mini review

G Seraphin, S Rieger, M Hewison… - The Journal of steroid …, 2023 - Elsevier
In this review, we summarize the most recent advances in vitamin D cancer research to
provide molecular clarity, as well as its translational trajectory across the cancer landscape …

Long non-coding RNA/epithelial-mesenchymal transition axis in human cancers: Tumorigenesis, chemoresistance, and radioresistance

M Hashemi, S Hajimazdarany, CD Mohan… - Pharmacological …, 2022 - Elsevier
Epithelial-to-mesenchymal transition (EMT) is a process that involves the transformation of
polarized epithelial cells to attain a mesenchymal phenotype that presents an elevated …

A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for niraparib

M Guo, Y Shu, G Chen, J Li, F Li - Scientific Reports, 2022 - nature.com
Niraparib was approved for the treatment of platinum-sensitive recurrent epithelial ovarian
cancer, fallopian tube and primary peritoneal cancer. The authors retrospectively …

Label-free electrochemical aptasensor based on magnetic α-Fe2O3/Fe3O4 heterogeneous hollow nanorods for the detection of cancer antigen 125

Y Ni, H Ouyang, L Yu, C Ling, Z Zhu, A He, R Liu - Bioelectrochemistry, 2022 - Elsevier
A label-free electrochemical aptasensor based on magnetic α-Fe 2 O 3/Fe 3 O 4
heterogeneous hollow nanorods was developed for the detection of cancer antigen 125 …

Host obesity alters the ovarian tumor immune microenvironment and impacts response to standard of care chemotherapy

Y Liu, J Yang, TS Hilliard, Z Wang, J Johnson… - Journal of Experimental …, 2023 - Springer
Background The majority of women with epithelial ovarian cancer (OvCa) are diagnosed
with metastatic disease, resulting in a poor 5-year survival of 31%. Obesity is a recognized …

Modulation of cisplatin sensitivity through TRPML1-mediated lysosomal exocytosis in ovarian cancer cells: a comprehensive metabolomic approach

B Kim, G Kim, H Kim, YS Song, J Jung - Cells, 2024 - mdpi.com
Background: The lysosome has emerged as a promising target for overcoming
chemoresistance, owing to its role in facilitating the lysosomal sequestration of drugs. The …

An overview of ovarian cancer: the role of cancer stem cells in chemoresistance and a precision medicine approach targeting the Wnt pathway with the antagonist …

L Varier, SM Sundaram, N Gamit, S Warrier - Cancers, 2023 - mdpi.com
Simple Summary Ovarian cancer is one of the deadliest cancers in women and is
unfortunately detected only in its later stages, by which time it will have metastasized to …

Identifying serum small extracellular vesicle MicroRNA as a noninvasive diagnostic and prognostic biomarker for ovarian cancer

L Li, F Zhang, J Zhang, X Shi, H Wu, X Chao, S Ma… - ACS …, 2023 - ACS Publications
There remains a lack of effective and noninvasive methods for the diagnosis and prognosis
prediction of epithelial ovarian carcinoma (EOC). Here, we investigated the possibility of …