Ultraviolet light and ocular diseases

JCS Yam, AKH Kwok - International ophthalmology, 2014 - Springer
The objective of this study is to review the association between ultraviolet (UV) light and
ocular diseases. The data are sourced from the literature search of Medline up to Nov 2012 …

Role of mitochondria in retinal pigment epithelial aging and degeneration

Y Tong, Z Zhang, S Wang - Frontiers in aging, 2022 - frontiersin.org
Retinal pigment epithelial (RPE) cells form a monolayer between the neuroretina and
choroid. It has multiple important functions, including acting as outer blood-retina barrier …

Free radical biology in neurological manifestations: mechanisms to therapeutics interventions

R Tripathi, R Gupta, M Sahu, D Srivastava… - … Science and Pollution …, 2021 - Springer
Recent advancements and growing attention about free radicals (ROS) and redox signaling
enable the scientific fraternity to consider their involvement in the pathophysiology of …

A review: role of ultraviolet radiation in age-related macular degeneration

KV Chalam, V Khetpal, R Rusovici, S Balaiya - Eye & contact lens, 2011 - journals.lww.com
Age-related macular degeneration (AMD) is a leading cause of blindness in the western
world. The retina is highly susceptible to photochemical damage from continuous exposure …

Detrimental Effects of UVB on Retinal Pigment Epithelial Cells and Its Role in Age‐Related Macular Degeneration

CK Mahendra, LTH Tan, P Pusparajah… - Oxidative Medicine …, 2020 - Wiley Online Library
Retinal pigment epithelial (RPE) cells are an essential part of the human eye because they
not only mediate and control the transfer of fluids and solutes but also protect the retina …

Quantitative action spectroscopy reveals ARPE19 sensitivity to ultraviolet radiation at 350 nm and 380 nm

G Anderson, A McLeod, P Bagnaninchi, B Dhillon - Scientific Reports, 2022 - nature.com
The role of ultraviolet radiation (UVR) exposure in the aetiology of retinal degeneration has
been debated for decades with epidemiological evidence failing to find a clear consensus …

Daily Light Onset and Plasma Membrane Tethers Regulate Mitochondria Redistribution within the Retinal Pigment Epithelium

MV Neto, G De Rossi, BA Berkowitz, MC Seabra… - Cells, 2024 - mdpi.com
The retinal pigment epithelium (RPE) is an essential component of the retina that plays
multiple roles required to support visual function. These include light onset-and circadian …

Photobiomodulation of the visual system and human health

J Buch, B Hammond - International Journal of Molecular Sciences, 2020 - mdpi.com
Humans express an expansive and detailed response to wavelength differences within the
electromagnetic (EM) spectrum. This is most clearly manifest, and most studied, with respect …

Development and Use of Retinal Pigmented Epithelial Cell Line from Zebrafish (Danio rerio) for Evaluating the Toxicity of Ultraviolet-B

KSN Nambi, S Abdul Majeed, G Taju, S Sivasubbu… - Zebrafish, 2015 - liebertpub.com
Danio rerio retinal pigmented epithelial (Dr RPE) cell line, derived from the RPE tissue, was
established and characterized. The cells were able to grow at a wide range of temperatures …

[HTML][HTML] Oxidative stress measures of lipid and DNA damage in human tears

KM Haworth, HL Chandler - Investigative Ophthalmology & …, 2017 - tvst.arvojournals.org
Purpose: We evaluate feasibility and repeatability of measures for lipid peroxidation and
DNA oxidation in human tears, as well as relationships between outcome variables, and …