Machilin D Promotes Apoptosis and Autophagy, and Inhibits Necroptosis in Human Oral Squamous Cell Carcinoma Cells
HM Yun, YJ Kwon, E Kim, HJ Chung… - International Journal of …, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) accounts for about 90% of all head and neck
cancers, the prognosis is very poor, and there are no effective targeted therapies. Herein, we …
cancers, the prognosis is very poor, and there are no effective targeted therapies. Herein, we …
Focal adhesion kinase: Insight into its roles and therapeutic potential in oesophageal cancer
Y Zhang, S Liu, S Zhou, D Yu, J Gu, Q Qin, Y Cheng… - Cancer letters, 2021 - Elsevier
Oesophageal cancer is associated with high morbidity and mortality rates because it is
highly invasive and prone to recurrence and metastasis, with a five-year survival rate of< …
highly invasive and prone to recurrence and metastasis, with a five-year survival rate of< …
Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination
MET exon 14 skipping alteration (METΔ14Ex) is an actionable oncogenic driver that occurs
in 2% to 4% of non–small cell lung cancer (NSCLC) cases. The precise role of METΔ14Ex in …
in 2% to 4% of non–small cell lung cancer (NSCLC) cases. The precise role of METΔ14Ex in …
Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma
G Del Mistro, S Riemann, S Schindler, S Beissert… - Cell death & …, 2022 - nature.com
Despite remarkable advances in therapeutic interventions, malignant melanoma (MM)
remains a life-threating disease. Following high initial response rates to targeted kinase …
remains a life-threating disease. Following high initial response rates to targeted kinase …
Human amniotic membrane inhibits migration and invasion of muscle-invasive bladder cancer urothelial cells by downregulating the FAK/PI3K/Akt/mTOR signalling …
Bladder cancer is the 10th most commonly diagnosed cancer with the highest lifetime
treatment costs. The human amniotic membrane (hAM) is the innermost foetal membrane …
treatment costs. The human amniotic membrane (hAM) is the innermost foetal membrane …
Progesterone promotes cell migration, invasion and cofilin activation in human astrocytoma cells
AG Piña-Medina, V Hansberg-Pastor… - Steroids, 2016 - Elsevier
Astrocytomas are the most common and aggressive primary brain tumors in humans.
Invasiveness of these tumors has been attributed in part to deregulation of cell motility …
Invasiveness of these tumors has been attributed in part to deregulation of cell motility …
Leptin promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-27b in human chondrosarcoma cells
Chondrosarcoma is the second most frequently occurring type of bone malignancy that is
characterized by the distant metastasis propensity. Vascular endothelial growth factor-C …
characterized by the distant metastasis propensity. Vascular endothelial growth factor-C …
Paeoniflorigenone regulates apoptosis, autophagy, and necroptosis to induce anti-cancer bioactivities in human head and neck squamous cell carcinomas
KR Park, H Lee, SH Kim, HM Yun - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Paonia suffruticosa Andr. belonging to the family
Paeoniaceae and has been used as a medicinal plant in Asian countries including China …
Paeoniaceae and has been used as a medicinal plant in Asian countries including China …
IntLIM: integration using linear models of metabolomics and gene expression data
JK Siddiqui, E Baskin, M Liu, CZ Cantemir-Stone… - BMC …, 2018 - Springer
Background Integration of transcriptomic and metabolomic data improves functional
interpretation of disease-related metabolomic phenotypes, and facilitates discovery of …
interpretation of disease-related metabolomic phenotypes, and facilitates discovery of …
Picturing breast cancer brain metastasis development to unravel molecular players and cellular crosstalk
I Figueira, S Galego, T Custódio-Santos, R Vicente… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is a devastating disorder affecting millions of women
worldwide. With improved therapeutics for the primary tumor, the appearance of metastasis …
worldwide. With improved therapeutics for the primary tumor, the appearance of metastasis …