Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

While knowledge of the composition and mode of action of bee and wasp venoms dates
back 50 years, the therapeutic value of these toxins remains relatively unexploded. The …

Venomous animals have evolved toxins that interfere with specific components of their
victim's core physiological systems, thereby causing biological dysfunction that aids in prey …

Lipidation is a posttranslational modification of proteins that has also found its use in
designing peptide drugs. The presence of a lipid group in peptides modulates their …

The emergence of antibiotic-resistant clinical isolates and the decreased rate of
development of new antibiotics are a constant threat to human health. In this context, the …

Cationic membrane-active peptides have been studied for years in the hope of developing
them into novel types of therapeutics. In this article, we investigate an effect that might have …

Staphylococcus aureus is a common pathogen that can cause pneumonia and a variety of
skin diseases. Skin injuries have a high risk of colonization by S. aureus, which increases …

The discovery of new anti-infective compounds is stagnating and multi-resistant bacteria
continue to emerge, threatening to end the “antibiotic era”. Antimicrobial peptides (AMPs) …

Polybia-MP1 is a well-known natural antimicrobial peptide that has been intensively studied
recently due to its therapeutic potential. MP1 exhibited not only potent antibacterial activity …

Development of antimicrobial peptides (AMPs) as highly effective and selective anticancer
agents would represent great progress in cancer treatment. Here we show that myristoyl …