Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …

Importance Discrepancies in oxygen saturation measured by pulse oximetry (Spo 2), when
compared with arterial oxygen saturation (Sao 2) measured by arterial blood gas (ABG) …

Aims Apnoea–hypopnoea index (AHI), the universal clinical metric of sleep apnoea severity,
poorly predicts the adverse outcomes of sleep apnoea, potentially because the AHI, a …

Sleep deprivation (SD) has become a relevant health problem in modern societies. We can
be sleep deprived due to lifestyle habits or due to sleep disorders, such as insomnia …

Obesity is a significant public health challenge worldwide and is inextricably linked to
adverse cardiovascular outcomes. The relationship between excess adiposity and …

Both oxidative stress and inflammation are enhanced in chronic heart failure. Dysfunction of
cardiac mitochondria is a hallmark of heart failure and a leading cause of oxidative stress …

Abstract Obesity contributes 65–75% of the risk for human primary (essential) hypertension
(HT) which is a major driver of cardiovascular and kidney diseases. Kidney dysfunction …

Intermittent hypoxia (IH) is a hallmark manifestation of obstructive sleep apnea (OSA), a
widespread disorder of breathing. This Review focuses on the role of hypoxia-inducible …

Obstructive sleep apnea (OSA) is characterised by recurring episodes of upper airway
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …