Progesterone as an anti-inflammatory drug and immunomodulator: new aspects in hormonal regulation of the inflammation

TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Biomolecules, 2022 - mdpi.com
The specific regulation of inflammatory processes by steroid hormones has been actively
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …

Progestins as anticancer drugs and chemosensitizers, new targets and applications

TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Pharmaceutics, 2021 - mdpi.com
Progesterone and its synthetic analogues, progestins, participate in the regulation of cell
differentiation, proliferation and cell cycle progression. Progestins are usually applied for …

The role of autophagy and apoptosis in the combined action of plasma-treated saline, doxorubicin, and medroxyprogesterone acetate on K562 myeloid leukaemia …

T Pavlik, V Gudkova, D Razvolyaeva… - International Journal of …, 2023 - mdpi.com
The anti-cancer properties of plasma-treated solutions (PTS) and their interaction with drugs
are one of the most popular topics in modern plasma medicine. Our research involved …

Hormonal contraceptives, stress, and the brain: The critical need for animal models

NC Tronson, KM Schuh - Frontiers in Neuroendocrinology, 2022 - Elsevier
Hormonal contraceptives are among the most important health and economic developments
in the 20th Century, providing unprecedented reproductive control and a range of health …

Understanding progestins: from basics to clinical applicability

M García-Sáenz, R Ibarra-Salce… - Journal of Clinical …, 2023 - mdpi.com
Progestin is a term used to describe a synthetic progestogen. The activity and potency of
synthetic progestins are mostly evaluated via parameters associated with their endometrial …

Feasibility and activity of megestrol acetate in addition to etoposide, doxorubicin, cisplatin, and mitotane as first-line therapy in patients with metastatic/unresectable …

A Turla, M Laganà, A Abate, V Cremaschi, M Zamparini… - Cancers, 2023 - mdpi.com
Simple Summary Preclinical studies have shown an anti-neoplastic effect of progestins
against adrenal cortical carcinoma. Progestins have a positive effect on patient cenesthesia …

An in-silico investigation and network pharmacology based approach to explore the anti-breast-cancer potential of Tecteria coadunata (Wall.) C. Chr.

S Ram, P More-Adate, AA Tagalpallewar… - Journal of …, 2023 - Taylor & Francis
Uncontrolled cell proliferation is a common definition of cancer. After lung carcinoma, breast
neoplasm is the second-most prevalent kind of cancer. The majority of breast cancer cells …

The environmental occurrence, fate, and risks of 25 endocrine disruptors in Slovenian waters

A Grobin, R Roškar, J Trontelj - Science of the Total Environment, 2024 - Elsevier
Natural hormones, synthetic steroids and bisphenols are among the most active endocrine
disruptors (EDs) in the aquatic environment, with great potential for causing adverse effects …

A mouse model of oral contraceptive exposure: Depression, motivation, and the stress response

KM Schuh, J Ahmed, E Kwak, CX Xu, TT Davis… - Hormones and …, 2024 - Elsevier
Hormonal contraceptives, including oral contraceptives (OCs), regulate hormonal cycles and
broadly affect physiological processes, including stress responsivity. Whereas many users …

Advances in molecularly imprinted polymers-based electrochemical sensors for the detection of gonadal steroid hormones

B Hu, L Peng, P Liang, X Li, M Cai, B Liu, Y Jia… - TrAC Trends in …, 2023 - Elsevier
The potential risks to human health posed by the overuse of gonadal steroid hormones
(GSH), make it essential to develop a sensitive method for monitoring their levels. Recently …