The knowns and unknowns of cardiac autoimmunity in viral myocarditis

K Mone, J Reddy - Reviews in Medical Virology, 2023 - Wiley Online Library
Myocarditis can result from various infectious and non‐infectious causes that can lead to
dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are …

Neural immunoglobulin superfamily interaction networks

K Zinn, E Özkan - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Mammalian IgSF subfamilies define small interaction networks.•A global
Drosophila IgSF interaction map identifies complex binding networks.•Large networks with …

Beyond passive immunity: is there priming of the fetal immune system following vaccination in pregnancy and what are the potential clinical implications?

CR Wilcox, CE Jones - Frontiers in immunology, 2018 - frontiersin.org
Infection is responsible for over half a million neonatal deaths worldwide every year, and
vaccination in pregnancy is becoming increasingly recognized as an important strategy for …

[HTML][HTML] Opportunities and challenges for antibodies against intracellular antigens

X Yang, S Xie, X Yang, JC Cueva, X Hou, Z Tang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Therapeutic antibodies are one most significant advances in immunotherapy, the
development of antibodies against disease-associated MHC-peptide complexes led to the …

Preparation of peptide–MHC and T-cell receptor dextramers by biotinylated dextran doping

MT Bethune, B Comin-Anduix, YHH Fu, A Ribas… - …, 2017 - Taylor & Francis
Peptide–major histocompatibility complex (pMHC) multimers enable the detection,
characterization, and isolation of antigen-specific T-cell subsets at the single-cell level via …

Enrichment and quantification of epitope-specific CD4+ T lymphocytes using ferromagnetic iron-gold and nickel nanowires

DE Shore, T Dileepan, JF Modiano, MK Jenkins… - Scientific reports, 2018 - nature.com
Epitope-specific CD4+ T lymphocytes were magnetically enriched using ferromagnetic Ni
and Fe-Au nanowires coated with a monomer containing a major histocompatibility complex …

Epitope mapping of SERCA2a identifies an antigenic determinant that induces mainly atrial myocarditis in A/J mice

B Krishnan, C Massilamany… - The Journal of …, 2018 - journals.aai.org
Sarcoplasmic/endoplasmic reticulum Ca 2+ adenosine triphosphatase (SERCA) 2a, a
critical regulator of calcium homeostasis, is known to be decreased in heart failure. Patients …

Designing personalized antigen-specific immunotherapies for autoimmune diseases—the case for using ignored target cell antigen determinants

J Tian, M Song, DL Kaufman - Cells, 2022 - mdpi.com
We have proposed that antigen-specific immunotherapies (ASIs) for autoimmune diseases
could be enhanced by administering target cell antigen epitopes (determinants) that are …

Assay and isolation of single proliferating CD4+ lymphocytes using an automated microraft array platform

CA LaBelle, RJ Zhang, PM Armistead… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
Objective: While T lymphocytes have been employed as a cancer immunotherapy, the
development of effective and specific T-cell-based therapeutics remains challenging. A key …

An evidence for surface expression of an immunogenic epitope of sarcoplasmic/endoplasmic reticulum calcium-ATPase2a on antigen-presenting cells from naive …

R Arumugam, B Yalaka, C Massilamany, MSSH Ali… - Immunobiology, 2020 - Elsevier
We recently reported identification of sarcoplasmic/endoplasmic reticulum calcium-
ATPase2a (SERCA2a) 971-990, which induces atrial myocarditis by generating autoreactive …