Intrahepatic cholestasis of pregnancy (ICP) is the most common, reversible, and closely
related to pregnancy condition characterized by elevated levels of bile acids (BAs) in blood …

Abstract Aflatoxin B1 (AFB1) is a common contaminant in many foodstuffs and is considered
a public health concern worldwide due to its hepatotoxicity caused by lipid metabolism …

Background: The placenta exerts a crucial role in fetus growth and development during
gestation, protecting the fetus from maternal drugs and chemical exposure. However …

Background Lipids serve as multifunctional metabolites that have important implications for
the pregnant mother and developing fetus. Abnormalities in lipids have emerged as …

Cholesterol trafficking is initiated by the endocytic pathway and transported from
endo/lysosomes to other intracellular organelles. Deficiencies in cholesterol-sensing and …

Bioethical limitations impair deeper studies in human placental physiology, then most
studies use human term placentas or murine models. To overcome these challenges, new …

In animals, cholesterol is an essential component of every cellular membrane and is
required for cell membrane integrity. Cholesterol is insoluble in water but is solubilized by …

Objective To determine and compare the serum metabolites in missed abortion versus
normal early pregnancy using ultra‐high‐performance liquid chromatography and tandem …

Introduction: During pregnancy, P4 is essential to maintain the maternal-fetal relationship.
Maternal cholesterol is the main source of P4 production, a process that takes place in the …

The genetic material encoded on X and Y chromosomes provides the foundation by which
biological sex differences are established. Epigenetic regulators expressed on these sex …