DNA methylation is a stable epigenetic mark that can be inherited through multiple cell
divisions. During development and cell differentiation, DNA methylation is dynamic, but …

Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …

Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …

Dysregulation of the epigenetic enzyme-mediated transcription of oncogenes or tumor
suppressor genes is closely associated with the occurrence, progression, and prognosis of …

Mesenchymal stromal cells (MSCs) have been considered a therapeutic strategy in
regenerative medicine because of their regenerative and immunomodulatory properties …

The biomedical applications of mesenchymal stem cells (MSCs) have gained expanding
attention over the past three decades. MSCs are easily obtained from various tissue types …

This review aims to give a brief summary of the most common epigenetic mechanisms, and
their possible relations with cancer initiation and progression, focusing on the possible …

Mesenchymal stromal cells (MSCs) have great value in cell therapies. The MSC therapies
have many challenges due to its inconsistent potency and limited quantity. Here, we report a …

Adult human bone marrow stromal cells (hBMSC) cultured for cell therapy require evaluation
of potency and stability for safe use. Chromosomal aberrations upsetting genomic integrity in …

During the two last decades, mesenchymal stromal cells (MSCs) have been topics of
intensive investigation due to their intriguing characteristics, which make them exciting …