Acinetobacter baumannii: human infections, factors contributing to pathogenesis and animal models

MJ McConnell, L Actis, J Pachón - FEMS microbiology reviews, 2013 - academic.oup.com
Acinetobacter baumannii has emerged as a medically important pathogen because of the
increasing number of infections produced by this organism over the preceding three …

[HTML][HTML] Multiresistant Acinetobacter baumannii infections: epidemiology and management

J Garnacho-Montero… - Current opinion in …, 2010 - journals.lww.com
The optimal treatment for multidrug-resistant A. baumannii nosocomial infections has not
been established. Carbapenems are the mainstay of treatment in susceptible isolates …

Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system

A Beceiro, E Llobet, J Aranda… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Colistin resistance is rare in Acinetobacter baumannii, and little is known about its
mechanism. We investigated the role of PmrCAB in this trait, using (i) resistant and …

[HTML][HTML] Comparison of colistin–carbapenem, colistin–sulbactam, and colistin plus other antibacterial agents for the treatment of extremely drug-resistant Acinetobacter …

A Batirel, II Balkan, O Karabay, C Agalar… - European journal of …, 2014 - Springer
The purpose of this investigation was to compare the efficacy of colistin-based therapies in
extremely drug-resistant Acinetobacter spp. bloodstream infections (XDR-ABSI). A …

Confronting multidrug-resistant Acinetobacter baumannii: a review

IK Neonakis, DA Spandidos, E Petinaki - International journal of …, 2011 - Elsevier
Multidrug-resistant Acinetobacter baumannii (MDR-AB) infections are difficult to treat owing
to the extremely limited armamentarium. The present review reports all available treatment …

[HTML][HTML] Advances in bacteriophage therapy against relevant multidrug-resistant pathogens

A Broncano-Lavado, G Santamaría-Corral, J Esteban… - Antibiotics, 2021 - mdpi.com
The increase of multiresistance in bacteria and the shortage of new antibiotics in the market
is becoming a major public health concern. The World Health Organization (WHO) has …

Distribution of the multidrug efflux pump genes, adeABC, adeDE and adeIJK, and class 1 integron genes in multiple-antimicrobial-resistant clinical isolates of …

L Lin, BD Ling, XZ Li - International journal of antimicrobial agents, 2009 - Elsevier
Of 112 non-repetitive clinical isolates of Acinetobacter baumannii–Acinetobacter
calcoaceticus complex, 80% were resistant to a variety of structurally unrelated …

Vaccination with Outer Membrane Complexes Elicits Rapid Protective Immunity to Multidrug-Resistant Acinetobacter baumannii

MJ McConnell, J Domínguez-Herrera… - Infection and …, 2011 - Am Soc Microbiol
Acinetobacter baumannii causes pneumonias, bacteremias, and skin and soft tissue
infections, primarily in the hospitalized setting. The incidence of infections caused by A …

Emerging therapies for multidrug resistant Acinetobacter baumannii

M García-Quintanilla, MR Pulido, R López-Rojas… - Trends in …, 2013 - cell.com
The global emergence of multidrug resistant Acinetobacter baumannii has reduced the
number of clinically available antibiotics that retain activity against this pathogen. For this …

Active and passive immunization against Acinetobacter baumannii using an inactivated whole cell vaccine

MJ McConnell, J Pachón - Vaccine, 2010 - Elsevier
The treatment of infections caused by Acinetobacter baumannii has become increasingly
complicated due to the emergence of highly resistant strains. In the present study we …