The neural addiction of cancer

C Magnon, H Hondermarck - Nature Reviews Cancer, 2023 - nature.com
The recently uncovered key role of the peripheral and central nervous systems in controlling
tumorigenesis and metastasis has opened a new area of research to identify innovative …

Anxiety and hippocampal neuronal activity: Relationship and potential mechanisms

M Ghasemi, M Navidhamidi, F Rezaei… - Cognitive, Affective, & …, 2022 - Springer
The hippocampus has been implicated in modulating anxiety. It interacts with a variety of
brain regions, both cortical and subcortical areas regulating emotion and stress responses …

Sleep loss and addiction

LA López-Muciño, F García-García… - Neuroscience & …, 2022 - Elsevier
Reducing sleep hours is a risk factor for developing cardiovascular, metabolic, and
psychiatric disorders. Furthermore, previous studies have shown that reduction in sleep time …

Event-based control of autonomic and emotional states by the anterior cingulate cortex

JK Seamans, SB Floresco - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Despite being an intensive area of research, the function of the anterior cingulate cortex
(ACC) remains somewhat of a mystery. Human imaging studies implicate the ACC in various …

Altered Brain Expression of DNA Methylation and Hydroxymethylation Epigenetic Enzymes in a Rat Model of Neuropathic Pain

D Rodrigues, C Monteiro, H Cardoso-Cruz… - International Journal of …, 2023 - mdpi.com
The role of epigenetics in chronic pain at the supraspinal level is yet to be fully
characterized. DNA histone methylation is crucially regulated by de novo methyltransferases …

Nociceptive Stimuli Activate the Hypothalamus–Habenula Circuit to Inhibit the Mesolimbic Reward System and Cocaine-Seeking Behaviors

SM Lee, HB Jang, Y Fan, BH Lee, SC Kim… - Journal of …, 2022 - Soc Neuroscience
Nociceptive signals interact with various regions of the brain, including those involved in
physical sensation, reward, cognition, and emotion. Emerging evidence points to a role of …

[HTML][HTML] Contribution of activating lateral hypothalamus-lateral habenula circuit to nerve trauma-induced neuropathic pain in mice

HW Gu, GF Zhang, PM Liu, WT Pan, YX Tao… - Neurobiology of …, 2023 - Elsevier
Neuropathic pain, a severe clinical symptom, significantly affects the quality of life in the
patients. The molecular mechanisms underlying neuropathic pain have been the focus of …

Brainwide input-output architecture of paraventricular oxytocin and vasopressin neurons

SN Freda, MF Priest, D Badong, L Xiao, Y Liu… - bioRxiv, 2022 - biorxiv.org
Oxytocin and vasopressin are pleiotropic neuropeptides with well-established roles in the
regulation of social behavior and homeostatic functions. Their structural similarity and …

[HTML][HTML] Lateral hypothalamic orexin neurons mediate the reward effects of pain relief induced by electroacupuncture

C Wang, M Chen, C Qin, X Qu, X Shen… - Frontiers in Molecular …, 2022 - frontiersin.org
The reward of pain relief caused by acupuncture has been found to be clinically significant.
However, the molecular mechanisms underlying acupuncture-induced reward of pain relief …

The hypothalamus as a key regulator of glucose homeostasis: emerging roles of the brain renin-angiotensin system

S Pan, CJ Worker… - American Journal of …, 2023 - journals.physiology.org
The regulation of plasma glucose levels is a complex and multifactorial process involving a
network of receptors and signaling pathways across numerous organs that act in concert to …