Precision medicine and personalized medicine are two approaches to healthcare that aim to
tailor medical treatments and interventions to individual patients. These approaches are …

Because genetic alterations including mutations, overexpression, translocations, and
dysregulation of protein kinases are involved in the pathogenesis of many illnesses, this …

The paper presents a review of models that can be used to describe dynamics of lung
cancer growth and its response to treatment at both cell population and intracellular …

Chronic obstructive pulmonary disease (COPD) is often associated with lung squamous cell
carcinoma (LUSC), which has the same etiology (smoking, inflammation, oxidative stress …

The emergence of targeted therapies in non-small-cell lung cancer (NSCLC), including
inhibitors of epidermal growth factor receptor (EGFR) tyrosine kinase, has increased the …

Background Personalized targeted therapies have transformed management of several
solid tumors. Timely and accurate detection of clinically relevant genetic variants in tumor is …

Background Targeted therapy is now the standard of care in driver–oncogene-positive non-
small cell lung cancer (NSCLC). Its initial clinical effects are remarkable. However, almost all …

Abstract Background The Affordable Care Act expanded Medicaid coverage for people with
low income in the United States. Expanded insurance coverage could promote more timely …

The identification of actionable biomarkers and development of targeted therapies have
revolutionized the field of lung cancer treatment. In patients with advanced non-small cell …

Background The primary reason for tumor‐related deaths worldwide is lung
adenocarcinoma (LUAD). The oncogene IQ motif‐containing GTPase activating protein 3 …