[HTML][HTML] Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Microbiota-mediated colonization resistance: mechanisms and regulation

G Caballero-Flores, JM Pickard, G Núñez - Nature Reviews …, 2023 - nature.com
A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …

The evolution and ecology of bacterial warfare

ET Granato, TA Meiller-Legrand, KR Foster - Current biology, 2019 - cell.com
Bacteria have evolved a wide range of mechanisms to harm and kill their competitors,
including chemical, mechanical and biological weapons. Here we review the incredible …

Bacterial antagonism in host-associated microbial communities

L García-Bayona, LE Comstock - Science, 2018 - science.org
BACKGROUND Microbial communities are ubiquitous on Earth. The microbiota of different
habitats are diverse and have distinct functional traits, but there are common ecological …

[HTML][HTML] Interbacterial mechanisms of colonization resistance and the strategies pathogens use to overcome them

MT Sorbara, EG Pamer - Mucosal immunology, 2019 - Elsevier
The communities of bacteria that reside in the intestinal tract are in constant competition
within this dynamic and densely colonized environment. At homeostasis, the equilibrium that …

Type VII secretion systems: structure, functions and transport models

A Rivera-Calzada, N Famelis, O Llorca… - Nature Reviews …, 2021 - nature.com
Type VII secretion systems (T7SSs) have a key role in the secretion of effector proteins in
non-pathogenic mycobacteria and pathogenic mycobacteria such as Mycobacterium …

The central role of interbacterial antagonism in bacterial life

SB Peterson, SK Bertolli, JD Mougous - Current Biology, 2020 - cell.com
The study of bacteria interacting with their environment has historically centered on
strategies for obtaining nutrients and resisting abiotic stresses. We argue this focus has …

Structure of a tripartite protein complex that targets toxins to the type VII secretion system

TA Klein, PY Shah, P Gkragkopoulou… - Proceedings of the …, 2024 - National Acad Sciences
Type VII secretion systems are membrane-embedded nanomachines used by Gram-positive
bacteria to export effector proteins from the cytoplasm to the extracellular environment. Many …

Human gut bacteria contain acquired interbacterial defence systems

BD Ross, AJ Verster, MC Radey, DT Schmidtke… - Nature, 2019 - nature.com
The human gastrointestinal tract consists of a dense and diverse microbial community, the
composition of which is intimately linked to health. Extrinsic factors such as diet and host …

Contact-dependent interbacterial antagonism mediated by protein secretion machines

TA Klein, S Ahmad, JC Whitney - Trends in microbiology, 2020 - cell.com
To establish and maintain an ecological niche, bacteria employ a wide range of pathways to
inhibit the growth of their microbial competitors. Some of these pathways, such as those that …