Treatment of lithium intoxication: facing the need for evidence

R Haussmann, M Bauer, S Von Bonin, P Grof… - International journal of …, 2015 - Springer
Lithium has been used as the gold standard in the treatment of major depressive and bipolar
disorders for decades. Due to its narrow therapeutic index, lithium toxicity is a common …

Lithium intoxication: incidence, clinical course and renal function–a population-based retrospective cohort study

M Ott, B Stegmayr… - Journal of …, 2016 - journals.sagepub.com
When prescribing lithium, the risk of toxicity remains a concern. In this study, we examined a
cohort of patients exposed to lithium between 1997 and 2013. The aims of this study were to …

The photoinitiator lithium phenyl (2, 4, 6-trimethylbenzoyl) phosphinate with exposure to 405 nm light is cytotoxic to mammalian cells but not mutagenic in bacterial …

AK Nguyen, PL Goering, RK Elespuru, S Sarkar Das… - Polymers, 2020 - mdpi.com
Lithium phenyl (2, 4, 6-trimethylbenzoyl) phosphinate (LAP) is a free radical photo-initiator
used to initiate free radical chain polymerization upon light exposure, and is combined with …

Lithium: a potential therapeutic strategy in obsessive–compulsive disorder by targeting the canonical WNT/β pathway

A Vallée, JN Vallée, Y Lecarpentier - Translational Psychiatry, 2021 - nature.com
Obsessive–compulsive disorder (OCD) is a neuropsychiatric disorder characterized b–y
recurrent and distinctive obsessions and/or compulsions. The etiologies remain unclear …

[HTML][HTML] Lithium toxicity

SA Hedya, A Avula, HD Swoboda - 2018 - europepmc.org
Objectives: Describe the pathophysiology of lithium toxicity. Review lithium toxicokinetics.
Summarize the treatment of lithium toxicity. Outline interprofessional team strategies for …

Management of lithium intoxication

N Murphy, L Redahan, J Lally - BJPsych Advances, 2023 - cambridge.org
Lithium is a gold standard maintenance treatment in bipolar affective disorder. It has a
narrow therapeutic range, and at higher serum lithium levels there is a risk of adverse effects …

A renoprotective role of chitosan against lithium-induced renal toxicity in rats

WM Aboulthana, NES Ibrahim - Bulletin of the National Research Centre, 2018 - Springer
Abstract Background Lithium (Li) is considered as the first therapeutic line for treatment of
bipolar affective disorders and manic-depressive illness. Renal toxicity can be categorized …

The effects of lithium administration on oxidant/antioxidant status in rats: biochemical and histomorphological evaluations

S Toplan, S Ozdemir, G Tanriverdi… - Biological trace element …, 2016 - Springer
Present study was planned to determine possible dose-dependent effects of lithium (Li) on
oxidant-antioxidant status and histomorphological changes in liver and kidney tissues. For …

Lithium and atypical antipsychotics: The possible WNT/β pathway target in glaucoma

A Vallée, JN Vallée, Y Lecarpentier - Biomedicines, 2021 - mdpi.com
Glaucoma is a progressive neurodegenerative disease that represents the major cause of
irreversible blindness. Recent findings have shown which oxidative stress, inflammation …

Reduced risk for hospitalization due to hyponatraemia in lithium treated patients: A Swedish population-based case–control study

H Falhammar, J Skov, J Calissendorff… - Journal of …, 2021 - journals.sagepub.com
Background: Many drugs used in psychiatry have been reported to cause hyponatraemia.
However, lithium may be an exception due to its potential for causing nephrogenic diabetes …