Central role of the trehalose biosynthesis pathway in the pathogenesis of human fungal infections: opportunities and challenges for therapeutic development

A Thammahong, S Puttikamonkul… - Microbiology and …, 2017 - Am Soc Microbiol
Invasive fungal infections cause significant morbidity and mortality in part due to a limited
antifungal drug arsenal. One therapeutic challenge faced by clinicians is the significant host …

Overexpression of the Trehalase Gene AtTRE1 Leads to Increased Drought Stress Tolerance in Arabidopsis and Is Involved in Abscisic Acid-Induced Stomatal …

H Van Houtte, L Vandesteene, L López-Galvis… - Plant …, 2013 - academic.oup.com
Introduction of microbial trehalose biosynthesis enzymes has been reported to enhance
abiotic stress resistance in plants but also resulted in undesirable traits. Here, we present an …

Gene expression analysis of strawberry achene and receptacle maturation using DNA microarrays

A Aharoni, AP O'Connell - Journal of experimental botany, 2002 - academic.oup.com
Large‐scale, single pass sequencing and parallel gene expression analysis using DNA
microarrays were employed for the comprehensive investigation of ripening in strawberry …

[HTML][HTML] A single active trehalose-6-P synthase (TPS) and a family of putative regulatory TPS-like proteins in Arabidopsis

L Vandesteene, M Ramon, K Le Roy, P Van Dijck… - Molecular plant, 2010 - cell.com
Higher plants typically do not produce trehalose in large amounts, but their genome
sequences reveal large families of putative trehalose metabolism enzymes. An important …

Trehalose and trehalase in Arabidopsis

J Muller, RA Aeschbacher, A Wingler, T Boller… - Plant …, 2001 - academic.oup.com
Trehalase is ubiquitous in higher plants. So far, indications concerning its function are
scarce, although it has been implicated in the detoxification of exogenous trehalose. A …

Gene families and evolution of trehalose metabolism in plants

JE Lunn - Functional Plant Biology, 2007 - CSIRO Publishing
The genomes of Arabidopsis thaliana L., rice (Oryza sativa L.) and poplar (Populus
trichocarpa Torr. & A. Gray) contain large families of genes encoding trehalose-phosphate …

Functional identification of a trehalose 6-phosphate phosphatase gene that is involved in transient induction of trehalose biosynthesis during chilling stress in rice

M Habibur Rahman Pramanik, R Imai - Plant molecular biology, 2005 - Springer
Trehalose serves as a stress protectant and/or reserve carbohydrate in a variety of
organisms including bacteria, yeast, and invertebrates. Recently, trace amounts of trehalose …

Expansive evolution of the trehalose-6-phosphate phosphatase gene family in Arabidopsis

L Vandesteene, L López-Galvis, K Vanneste… - Plant …, 2012 - academic.oup.com
Trehalose is a nonreducing sugar used as a reserve carbohydrate and stress protectant in a
variety of organisms. While higher plants typically do not accumulate high levels of …

[HTML][HTML] Anhydrobiosis without trehalose in bdelloid rotifers

J Lapinski, A Tunnacliffe - FEBS letters, 2003 - Elsevier
Eukaryotes able to withstand desiccation enter a state of suspended animation known as
anhydrobiosis, which is thought to require accumulation of the non-reducing disaccharides …

Induction of Trehalase in Arabidopsis Plants Infected With the Trehalose-Producing Pathogen Plasmodiophora brassicae

D Brodmann, A Schuller… - Molecular plant …, 2002 - Am Phytopath Society
Various microorganisms produce the disaccharide trehalose during their symbiotic and
pathogenic interactions with plants. Trehalose has strong effects on plant metabolism and …