DEAD/H-box proteins are the largest family of RNA helicases in mammalian genomes, and
they are present in all kingdoms of life. Since their discovery in the late 1980s, DEAD/H-box …

Werner Syndrome (WS) is an autosomal recessive disorder characterized by premature
aging due to mutations of the WRN gene. A classical sign in WS patients is short stature, but …

Hereditary Breast and Ovarian Cancer (HBOC) syndrome is an autosomal dominant disease
associated with a high risk of developing breast, ovarian, and other malignancies. Lynch …

Background Multiple myeloma (MM), characterized by extensive genomic instability and
aberrant DNA damage repair, is a plasma cell malignancy due to the excessive proliferation …

El presente trabajo tuvo como finalidad evaluar la interacción in vivo, mediante ensayos de
pull-down, de la proteína de Werner (WRN), con los ARNm totales, ambos aislados de …

Werner Syndrome (WS) is an autosomal recessive disease which is characterized by
accelerated aging phenotypes, such as short stature, dyslipidemia, the loss of subcutaneous …

El propósito de la presente investigación fue evaluar la existencia de un vínculo funcional
entre WRN y componentes de la maquinaria de transporte de los ARNm, que pudiera …