[HTML][HTML] Myotonic dystrophy type 1

TD Bird - 2021 - europepmc.org
Myotonic dystrophy type 1 (DM1) is a multisystem disorder that affects skeletal and smooth
muscle as well as the eye, heart, endocrine system, and central nervous system. The clinical …

Drosophila Heart as a Model for Cardiac Development and Diseases

A Souidi, K Jagla - Cells, 2021 - mdpi.com
The Drosophila heart, also referred to as the dorsal vessel, pumps the insect blood, the
hemolymph. The bilateral heart primordia develop from the most dorsally located …

Clinical care recommendations for cardiologists treating adults with myotonic dystrophy

EM McNally, DL Mann, Y Pinto, D Bhakta… - Journal of the …, 2020 - Am Heart Assoc
Myotonic dystrophy is an inherited systemic disorder affecting skeletal muscle and the heart.
Genetic testing for myotonic dystrophy is diagnostic and identifies those at risk for cardiac …

Cardiac pathology in myotonic dystrophy type 1

MS Mahadevan, RS Yadava, M Mandal - International journal of …, 2021 - mdpi.com
Myotonic dystrophy type 1 (DM1), the most common muscular dystrophy affecting adults and
children, is a multi-systemic disorder affecting skeletal, cardiac, and smooth muscles as well …

Sudden cardiac death in neuromuscular disorders

J Finsterer, C Stöllberger, C Maeztu - International journal of cardiology, 2016 - Elsevier
Objectives The heart is frequently affected in neuromuscular disorders (NMDs). Some of
these patients even experience sudden cardiac death (SCD). In the following review, we …

Pentamidine rescues contractility and rhythmicity in a Drosophila model of myotonic dystrophy heart dysfunction

M Chakraborty, E Selma-Soriano… - Disease models & …, 2015 - journals.biologists.com
Up to 80% of individuals with myotonic dystrophy type 1 (DM1) will develop cardiac
abnormalities at some point during the progression of their disease, the most common of …

Subclinical cardiac involvement present as electrocardiographic abnormalities in various neuromuscular diseases

N Xiong, W Liu, J Li, S Luo, W Gu, W Zhu, J Xi, J Lin… - Heliyon, 2023 - cell.com
Background Cardiac involvement is commonly present in various neuromuscular diseases
which may develop life-threatening consequences. The early manifestation is often …

Dissecting Pathogenetic Mechanisms and Therapeutic Strategies in Drosophila Models of Myotonic Dystrophy Type 1

A Souidi, M Zmojdzian, K Jagla - International Journal of Molecular …, 2018 - mdpi.com
Myotonic dystrophy type 1 (DM1), the most common cause of adult-onset muscular
dystrophy, is autosomal dominant, multisystemic disease with characteristic symptoms …

Heart disease in disorders of muscle, neuromuscular transmission, and the nerves

J Finsterer, C Stöllberger - Korean circulation journal, 2016 - synapse.koreamed.org
Little is known regarding cardiac involvement (CI) by neuromuscular disorders (NMDs). The
purpose of this review is to summarise and discuss the major findings concerning the types …

[HTML][HTML] Cardiac involvement and arrhythmias associated with myotonic dystrophy

D McBride, A Deshmukh, S Shore… - Reviews in …, 2022 - ncbi.nlm.nih.gov
Myotonic dystrophy is an autosomal dominant genetic disease of nucleotide expansion
resulting in neuromuscular disease with two distinct subtypes. There are significant systemic …