Glaucoma comprises a group of progressive, neurodegenerative disorders characterized by
retinal ganglion cell death and nerve fiber layer atrophy. Several randomized controlled …

Abstract Abstract Bimatoprost (Lumigan®) is a synthetic prostamide that reduces intraocular
pressure (IOP) by increasing the outflow of aqueous humour. In patients with open-angle …

To determine the conditions under which anesthetized pigs can be used in acute
noninvasive investigations of ocular hydro-and hemodynamics, the intraocular pressure …

Background To report the clinical outcomes in Chinese patients with primary open-angle
glaucoma and ocular hypertension treated with bimatoprost 0.03% therapy. Methods Two …

Summary Abstract Topically administered bimatoprost 0.03%/timolol 0.5% ophthalmic
solution (bimatoprost/timolol: Ganfort®) comprises the synthetic prostamide bimatoprost …

Background: The β adrenergic receptors (ADRB) are expressed in the ciliary body and
trabecular meshwork, structures involved in aqueous humor production and outflow …

Objective This study aimed to compare the therapeutic efficacy and safety of
dorzolamide/timolol fixed-combination (Cosopt) in newly diagnosed primary open-angle …

Abstract▲ Brinzolamide 1%/timolol 0.5% fixed combination (brinzolamide/timolol) is a twice-
daily eyedrops suspension comprising the carbonic anhydrase-II inhibitor brinzolamide and …

Purpose: To characterize dose and response for intraocular pressure (IOP) reduction and
incidence of hyperemia using a model-based meta-analysis of IOP-lowering monotherapy …

Abstract Background Prostaglandin analogs (PGAs) are the first-line treatment for primary
open-angle glaucoma (POAG) and ocular hypertension (OH). This study aimed to confirm …