Active brown adipose tissue is associated with a healthier metabolic phenotype in obesity

CT Herz, OC Kulterer, M Prager, C Schmöltzer… - Diabetes, 2022 - Am Diabetes Assoc
Obesity is associated with increasing cardiometabolic morbidity and mortality rates
worldwide. Not everyone with obesity, however, develops metabolic complications. Brown …

[HTML][HTML] PNPLA3—a potential therapeutic target for personalized treatment of chronic liver disease

XC Dong - Frontiers in medicine, 2019 - frontiersin.org
Patatin-like phospholipase domain-containing protein 3 (PNPLA3) is a lipid droplet-
associated protein that has been shown to have hydrolase activity toward triglycerides and …

Non-alcoholic fatty liver disease, insulin resistance, metabolic syndrome and their association with vascular risk

E Muzurović, DP Mikhailidis, C Mantzoros - Metabolism, 2021 - Elsevier
The prevalence of non-alcoholic fatty liver disease (NAFLD), one of the most common liver
diseases, is rising. About 25% of adults worldwide are probably affected by NAFLD. Insulin …

Cardiometabolic health outcomes associated with discordant visceral and liver fat phenotypes: insights from the Dallas Heart Study and UK Biobank

S Tejani, C McCoy, CR Ayers, TM Powell-Wiley… - Mayo Clinic …, 2022 - Elsevier
Objective To evaluate the cardiometabolic outcomes associated with discordant visceral
adipose tissue (VAT) and liver fat (LF) phenotypes in 2 cohorts. Patients and Methods …

[PDF][PDF] Combination of tofogliflozin and pioglitazone for NAFLD: extension to the ToPiND randomized controlled trial

M Yoneda, T Kobayashi, Y Honda… - Hepatology …, 2022 - Wiley Online Library
The incidence of nonalcoholic fatty liver disease (NAFLD) has recently increased and is
related to obesity and the associated surge in type 2 diabetes mellitus (T2DM) and …

Causality between non‐alcoholic fatty liver disease and risk of cardiovascular disease and type 2 diabetes: A meta‐analysis with bias analysis

AE Morrison, F Zaccardi, K Khunti… - Liver …, 2019 - Wiley Online Library
Background & Aims A causal association of non‐alcoholic fatty liver disease (NAFLD) with
cardiovascular disease (CVD) and type 2 diabetes (T2DM) remains unproved. We aimed to …

[HTML][HTML] Non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus: a position statement of the Fatty Liver Research Group of the Korean Diabetes …

BW Lee, Y Lee, CY Park, EJ Rhee… - Diabetes & …, 2020 - synapse.koreamed.org
This clinical practice position statement, a product of the Fatty Liver Research Group of the
Korean Diabetes Association, proposes recommendations for the diagnosis, progression …

[HTML][HTML] Nonalcoholic fatty liver disease and endocrine axes—a scoping review

M Von-Hafe, M Borges-Canha, C Vale, AR Leite… - Metabolites, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease.
NAFLD often occurs associated with endocrinopathies. Evidence suggests that endocrine …

Epidemiology of Metabolic Dysfunction Associated Steatotic Liver Disease

ZM Younossi, M Kalligeros, L Henry - Clinical and Molecular Hepatology, 2024 - e-cmh.org
As the rates of obesity and type 2 diabetes (T2D) continue to increase globally, so does the
prevalence of metabolic dysfunction associated steatotic liver disease (MASLD). Currently …

[HTML][HTML] Comparing the diagnostic criteria of MAFLD and NAFLD in the Chinese population: a population-based prospective cohort study

C Yu, M Wang, S Zheng, M Xia, H Yang… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
Methods Based on the Jinchang cohort, 30,633 participants were collected. The prevalence
and incidence of MAFLD and NAFLD were used to analyze the epidemic characteristics and …