Hearing impairment is one of the most widespread inheritable sensory disorder affecting at
least 1 in every 1000 born. About two‐third of hereditary hearing loss (HHL) disorders are …

Background: Branchio-oto-renal syndrome (BOR) and branchio-oto syndrome (BOS) are
rare autosomal dominant disorders defined by varying combinations of branchial, otic, and …

Hearing loss (HL), both syndromic (SHL) and non-syndromic (NSHL), is the most common
sensory disorder, affecting~ 460 million people worldwide. More than 50% of the …

Some patients have an atypical form of branchio-oto-renal (BOR) syndrome, which does not
satisfy the diagnostic criteria, despite carrying a pathogenic variant (P variant) or a likely …

Hearing loss is the most frequent sensorineural disorder, affecting approximately 1: 1000
newborns. Hereditary forms (HHL) represent 50–60% of cases, highlighting the relevance of …

Congenital hearing loss is one of the most common sensory disabilities worldwide. The
genetic causes of hearing loss account for 50% of hearing loss. Genetic causes of hearing …

Waardenburg syndrome (WS) is a prevalent hearing loss syndrome, concomitant with focal
skin pigmentation abnormalities, blue iris, and other abnormalities of neural crest-derived …

Hereditary hearing loss (HL) has high genetic and phenotypical heterogeneity including the
overlapping and variable phenotypic features. For sporadic HL without a family history, it is …

Hearing impairment (HI) is a prevalent neurosensory condition globally, impacting 5% of the
population, with over 50% of congenital cases attributed to genetic etiologies. In Tunisia, HI …

Pendred syndrome (PDS) is the most common form of syndromic Hearing Loss (HL),
characterized by sensorineural HL, inner ear malformations, and goiter, with or without …