Recent trends in protective textiles against biological threats: A focus on biological warfare agents

JC Antunes, IP Moreira, F Gomes, F Cunha… - Polymers, 2022 - mdpi.com
The rising threats to worldwide security (affecting the military, first responders, and civilians)
urge us to develop efficient and versatile technological solutions to protect human beings …

Plague prevention and therapy: perspectives on current and future strategies

R Rosario-Acevedo, SS Biryukov, JA Bozue, CK Cote - Biomedicines, 2021 - mdpi.com
Plague, caused by the bacterial pathogen Yersinia pestis, is a vector-borne disease that has
caused millions of human deaths over several centuries. Presently, human plague infections …

A bacteriophage-based, highly efficacious, needle-and adjuvant-free, mucosal COVID-19 vaccine

J Zhu, S Jain, J Sha, H Batra, N Ananthaswamy… - MBio, 2022 - Am Soc Microbiol
ABSTRACT The US Food and Drug Administration-authorized mRNA-and adenovirus-
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …

[HTML][HTML] Yersinia pestis and Plague: Some knowns and unknowns

R Yang, S Atkinson, Z Chen, Y Cui, Z Du… - Zoonoses (Burlington …, 2023 - ncbi.nlm.nih.gov
Since its first identification in 1894 during the third pandemic in Hong Kong, there has been
significant progress of understanding the lifestyle of Yersinia pestis, the pathogen that is …

A modified recombinant adenovirus vector containing dual rabies virus G expression cassettes confers robust and long-lasting humoral immunity in mice, cats, and …

Y Zhang, L Fang, Z Wang, C Zhang, J Zhao… - Emerging Microbes & …, 2024 - Taylor & Francis
During the COVID-19 epidemic, the incidence of rabies has increased in several countries,
especially in remote and disadvantaged areas, due to inadequate surveillance and …

[HTML][HTML] The use of adenoviral vectors in gene therapy and vaccine approaches

NM Araújo, IGS Rubio, NPA Toneto… - … and Molecular Biology, 2022 - SciELO Brasil
Adenovirus was first identified in the 1950s and since then this pathogenic group of viruses
has been explored and transformed into a genetic transfer vehicle. Modification or deletion …

Pneumonic Plague Protection Induced by a Monophosphoryl Lipid A Decorated Yersinia Outer‐Membrane‐Vesicle Vaccine

S Majumder, S Das, P Li, N Yang, H Dellario, H Sui… - Small, 2024 - Wiley Online Library
A new Yersinia pseudotuberculosis mutant strain, YptbS46, carrying the lpxE insertion and
pmrF‐J deletion is constructed and shown to exclusively produce monophosphoryl lipid A …

Biodefence research two decades on: worth the investment?

CM Long, A Marzi - The Lancet Infectious Diseases, 2021 - thelancet.com
For the past 20 years, the notion of bioterror has been a source of considerable fear and
panic worldwide. In response to the terror attacks of 2001 in the USA, extensive research …

Optimised Heterologous Expression and Functional Analysis of the Yersinia pestis F1-Capsular Antigen Regulator Caf1R

DK Gahlot, G Ifill, S MacIntyre - International Journal of Molecular …, 2021 - mdpi.com
The bacterial pathogen, Yersinia pestis, has caused three historic pandemics and continues
to cause small outbreaks worldwide. During infection, Y. pestis assembles a capsule-like …

Combinatorial viral vector-based and live attenuated vaccines without an adjuvant to generate broader immune responses to effectively combat pneumonic plague

PB Kilgore, J Sha, EK Hendrix, VL Motin, AK Chopra - Mbio, 2021 - Am Soc Microbiol
Mice immunized with a combination of an adenovirus vector (Ad5-YFV) and live-attenuated
(LMA)-based vaccines were evaluated for protective efficacy against pneumonic plague …