Probiotics mechanism of action on immune cells and beneficial effects on human health

C Mazziotta, M Tognon, F Martini, E Torreggiani… - Cells, 2023 - mdpi.com
Immune cells and commensal microbes in the human intestine constantly communicate with
and react to each other in a stable environment in order to maintain healthy immune …

Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Z Celebi Sozener, B Ozdel Ozturk, P Cerci, M Turk… - Allergy, 2022 - Wiley Online Library
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Pathogenesis of pneumonia and acute lung injury

ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

Regulation of immune responses by the airway epithelial cell landscape

RJ Hewitt, CM Lloyd - Nature Reviews Immunology, 2021 - nature.com
The community of cells lining our airways plays a collaborative role in the preservation of
immune homeostasis in the lung and provides protection from the pathogens and pollutants …

Genomic diversity of severe acute respiratory syndrome–coronavirus 2 in patients with coronavirus disease 2019

Z Shen, Y Xiao, L Kang, W Ma, L Shi… - Clinical infectious …, 2020 - academic.oup.com
Background A novel coronavirus (CoV), severe acute respiratory syndrome (SARS)–CoV-2,
has infected> 75 000 individuals and spread to> 20 countries. It is still unclear how fast the …

Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

KL Bowerman, SF Rehman, A Vaughan… - Nature …, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is the third commonest cause of death
globally, and manifests as a progressive inflammatory lung disease with no curative …

Mucosa-interfacing electronics

K Nan, VR Feig, B Ying, JG Howarth, Z Kang… - Nature Reviews …, 2022 - nature.com
The surface mucosa that lines many of our organs houses myriad biometric signals and,
therefore, has great potential as a sensor–tissue interface for high-fidelity and long-term …

[HTML][HTML] Microbes, metabolites, and the gut–lung axis

AT Dang, BJ Marsland - Mucosal immunology, 2019 - Elsevier
The microbiota plays an essential role in the education, development, and function of the
immune system, both locally and systemically. Emerging experimental and epidemiological …

[HTML][HTML] Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer

M Zagorulya, L Yim, DM Morgan, A Edwards… - Immunity, 2023 - cell.com
Local environmental factors influence CD8+ T cell priming in lymph nodes (LNs). Here, we
sought to understand how factors unique to the tumor-draining mediastinal LN (mLN) impact …

The influence of the microbiome on respiratory health

TP Wypych, LC Wickramasinghe, BJ Marsland - Nature immunology, 2019 - nature.com
The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …