Developing an experimental-computational workflow to study the biomechanics of the human conventional aqueous outflow pathway
The aqueous humor actively interacts with the trabecular meshwork (TM), juxtacanalicular
tissue (JCT), and Schlemm's canal (SC) through a dynamic fluid-structure interaction (FSI) …
tissue (JCT), and Schlemm's canal (SC) through a dynamic fluid-structure interaction (FSI) …
Cell‐Derived Matrix: Production, Decellularization, and Application of Wound Repair
Y Xu, Y Yao, J Gao - Stem Cells International, 2024 - Wiley Online Library
Chronic nonhealing wounds significantly reduce patients' quality of life and are a major
burden on healthcare systems. Over the past few decades, tissue engineering materials …
burden on healthcare systems. Over the past few decades, tissue engineering materials …
Implementing new computational methods for the study of JCT and SC inner wall basement membrane biomechanics and hydrodynamics
Purpose The conventional aqueous outflow pathway, which includes the trabecular
meshwork (TM), juxtacanalicular tissue (JCT), and the inner wall endothelium of Schlemm's …
meshwork (TM), juxtacanalicular tissue (JCT), and the inner wall endothelium of Schlemm's …
Biomechanics of the JCT and SC Inner Wall Endothelial Cells with Their Basement Membrane Using 3D Serial Block-Face Scanning Electron Microscopy
Background: More than~ 70% of the aqueous humor exits the eye through the conventional
aqueous outflow pathway that is comprised of the trabecular meshwork (TM) …
aqueous outflow pathway that is comprised of the trabecular meshwork (TM) …
Comparative analysis of traction forces in normal and glaucomatous trabecular meshwork cells within a 3D, active fluid-structure interaction culture environment
This study presents a 3D in vitro cell culture model, meticulously 3D printed to replicate the
conventional aqueous outflow pathway anatomical structure, facilitating the study of …
conventional aqueous outflow pathway anatomical structure, facilitating the study of …
Segmental biomechanics of the normal and glaucomatous human aqueous outflow pathway
The conventional aqueous outflow pathway, encompassing the trabecular meshwork (TM),
juxtacanalicular connective tissue (JCT), and inner wall endothelium of Schlemm's canal …
juxtacanalicular connective tissue (JCT), and inner wall endothelium of Schlemm's canal …
Cryo-Electrospinning Generates Highly Porous Fiber Scaffolds Which Improves Trabecular Meshwork Cell Infiltration
DJ Crouch, CM Sheridan, JG Behnsen… - Journal of Functional …, 2023 - mdpi.com
Human trabecular meshwork is a sieve-like tissue with large pores, which plays a vital role
in aqueous humor outflow. Dysfunction of this tissue can occur, which leads to glaucoma …
in aqueous humor outflow. Dysfunction of this tissue can occur, which leads to glaucoma …
Effects of Schlemm's Canal Suture Implantation Surgery and Pilocarpine Eye Drops on Trabecular Meshwork Pulsatile Motion
Q Sang, R Du, C Xin, N Wang - Biomedicines, 2023 - mdpi.com
The trabecular meshwork is an important structure in the outflow pathway of aqueous humor,
and its movement ability directly affects the resistance of aqueous humor outflow, thereby …
and its movement ability directly affects the resistance of aqueous humor outflow, thereby …
[PDF][PDF] INVESTIGATIONS OF SIGMA-1 RECEPTOR AS A NOVEL THERAPEUTIC TARGET FOR GLAUCOMA IN PRECLINICAL MODELS
NM Tran - 2023 - repo.lib.semmelweis.hu
Glaucoma is a chronic progressive degenerative optic neuropathy that is the leading causes
of irreversible blindness worldwide. Glaucomatous optic neuropathies are associated with …
of irreversible blindness worldwide. Glaucomatous optic neuropathies are associated with …