Involvement of cell-derived extracellular particles, coined as matrix vesicles (MVs), in
biological bone formation was introduced by Bonucci and Anderson in mid-1960s. In 1983 …

Bone is a biomechanical tissue shaped by forces from muscles and gravitation.
Simultaneous bone and muscle decay and dysfunction (osteosarcopenia or sarco …

Despite its rigid structure, the bone is a dynamic organ, and is highly regulated by endocrine
factors. One of the major bone regulatory hormones is vitamin D. Its renal metabolite 1α, 25 …

Bone is a dynamic tissue that is strongly influenced by endocrine factors to restore the
balance between bone resorption and bone formation. Bone formation involves the …

The biological effects of 1α, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3) on osteoblast
differentiation and function differ significantly depending upon the cellular state of …

Tendon-to-bone healing after rotator cuff repair surgery has a failure rate of 20%–94%.
There has been a recent interest to determine the factors that act as determinants between …

The bioactive form of vitamin D [1, 25 (OH) 2 D 3] regulates mineral and bone homeostasis
and exerts potent anti-inflammatory and antiproliferative properties through binding to the …

Postkidney transplant hyperparathyroidism is a significant problem. Vitamin D receptor
agonists are known to suppress parathyroid hormone (PTH) secretion. We examined the …

Vitamin D is an important factor in bone metabolism. Animal studies have shown a positive
effect of vitamin D3 supplementation on fracture healing, but evidence from clinical trials is …

Previous randomized controlled trials have reported inconsistent findings regarding the
effects of high-dose vitamin D supplementation on a risk of falls and fractures. This meta …