The cellular and molecular bases of leptin and ghrelin resistance in obesity

H Cui, M López, K Rahmouni - Nature Reviews Endocrinology, 2017 - nature.com
Obesity, a major risk factor for the development of diabetes mellitus, cardiovascular diseases
and certain types of cancer, arises from a chronic positive energy balance that is often due to …

Leptin in inflammation and autoimmunity

A La Cava - Cytokine, 2017 - Elsevier
After its discovery as a key controller of metabolic function, leptin has been later extensively
implicated in additional functions including important modulatory activities on the innate and …

Aging and Alzheimer's disease: comparison and associations from molecular to system level

X Xia, Q Jiang, J McDermott, JDJ Han - Aging cell, 2018 - Wiley Online Library
Alzheimer's disease is the most prevalent cause of dementia, which is defined by the
combined presence of amyloid and tau, but researchers are gradually moving away from the …

Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

FM Davis, LC Tsoi, WJ Melvin, A DenDekker… - Journal of Experimental …, 2021 - rupress.org
Abdominal aortic aneurysms (AAAs) are a life-threatening disease for which there is a lack
of effective therapy preventing aortic rupture. During AAA formation, pathological vascular …

Leptin action in normal and pathological pregnancies

A Pérez‐Pérez, A Toro… - Journal of cellular …, 2018 - Wiley Online Library
Leptin is now considered an important signalling molecule of the reproductive system, as it
regulates the production of gonadotrophins, the blastocyst formation and implantation, the …

Association of atopic dermatitis with being overweight and obese: a systematic review and metaanalysis

A Zhang, JI Silverberg - Journal of the American Academy of Dermatology, 2015 - Elsevier
Background Previous studies found conflicting results about whether atopic dermatitis (AD)
is associated with overweight/obesity. Objective We sought to examine the relationship …

[图书][B] Robbins y Cotran. Patología estructural y funcional

V Kumar, AK Abbas, JC Aster - 2021 - books.google.com
Nueva edición del tratado de referencia en la disciplina que expone los fundamentos de la
anatomía patológica con un formato atractivo y de fácil consulta, que garantiza el acceso a …

[HTML][HTML] Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans

SN Meydani, SK Das, CF Pieper, MR Lewis… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
Calorie restriction (CR) inhibits inflammation and slows aging in many animal species, but in
rodents housed in pathogen-free facilities, CR impairs immunity against certain pathogens …

Recent advances in understanding leptin signaling and leptin resistance

DL Morris, L Rui - American Journal of Physiology …, 2009 - journals.physiology.org
The brain controls energy homeostasis and body weight by integrating various metabolic
signals. Leptin, an adipose-derived hormone, conveys critical information about peripheral …

Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease

SS Martin, A Qasim, MP Reilly - Journal of the American College of …, 2008 - jacc.org
Leptin is an adipocyte-derived hormone and cytokine that regulates energy balance through
a wide range of functions, including several that are important to cardiovascular health …