Because studies of the association between tricyclic antidepressant (TCA) treatment and risk
of fracture have shown inconsistent findings, we sought to assess whether people who take …

Measurement of serum testosterone (T) levels is recommended in the evaluation of
osteoporosis in older men and estradiol (E2) and sex hormone binding globulin (SHBG) …

ABSTRACT A significant link between cardiovascular disease and osteoporosis is
established in postmenopausal women, but data for men are scarce. We tested the …

Background Higher serum cystatin C level is associated with an increased risk of hip fracture
in postmenopausal white women, but there is a paucity of data for men. Whether estimated …

Androgen deprivation therapy (ADT) is part of standard therapy for locally advanced or
metastatic prostate cancer and is frequently used in men with a rising prostate-specific …

The monoamine serotonin (5-hydroxytryptamine, 5-HT), a well-known neurotransmitter, also
has important functions outside the central nervous system. The objective of this study was …

This document is an update of the clinical guideline published by the National Osteoporosis
Foundation of South Africa (NOFSA) in 2000, which aims to improve the overall efficacy of …

Clinically, these findings should imply greater emphasis on high impact exercise during
skeletal growth and on maintenance of weight bearing and balance training in the later …

Use of antidepressant medications has been associated with increased risk of fracture, but
prior studies have been limited by incomplete control of confounders or a limited number of …

Introduction angiotensin II, a major effector protein of the renin angiotensin system (RAS),
induces bone loss under certain conditions. Drugs that block the RAS may therefore reduce …