[HTML][HTML] Theranostic small-molecule prodrug conjugates for targeted delivery and controlled release of toll-like receptor 7 agonists

S Debnath, G Hao, B Guan, P Thapa, J Hao… - International journal of …, 2022 - mdpi.com
We previously reported the design and synthesis of a small-molecule drug conjugate
(SMDC) platform that demonstrated several advantages over antibody–drug conjugates …

86Y-labeled albumin-binding fibroblast activation protein inhibitor for late-time-point cancer diagnosis

J Ding, M Xu, J Chen, P Zhang, L Huo… - Molecular …, 2022 - ACS Publications
Fibroblast activation protein inhibitor (FAPI) is a novel quinoline-based radiopharmaceutical
that has theranostic potential, yet the limited tumor retention hinders late-time diagnosis and …

A Review on Novel Applications of Nanotechnology in the Management of Prostate Cancer

A Khanam, G Singh, S Narwal, B Chopra… - Current Drug …, 2024 - ingentaconnect.com
Background: Prostate cancer continues to be a serious danger to men's health, despite
advances in the field of cancer nanotechnology. Although different types of cancer have …

[HTML][HTML] Investigation of the Effect on the Albumin Binding Moiety for the Pharmacokinetic Properties of 68Ga-, 205/206Bi-, and 177Lu-Labeled NAPamide-Based …

D Szücs, JP Szabó, V Arató, B Gyuricza, D Szikra… - Pharmaceuticals, 2023 - mdpi.com
Although radiolabeled alpha-melanocyte stimulating hormone-analogue NAPamide
derivatives are valuable melanoma-specific diagnostic probes, their rapid elimination …

The development of cyclotron-based radiopharmaceuticals: a comprehensive review of 64Cu and 123I-radiolabeled urea-based small molecule PSMA ligands

LA Hasnowo, MS Larkina, AA Garapatski… - … of Radioanalytical and …, 2023 - Springer
Abstract 64Cu and 123I are attracting attention in taking up their role in the development and
practical use of PSMA-targeting radiopharmaceuticals. The development of urea-based …

Safety Evaluation of 177 Lu-TEFAPI-06 with Long-Term Blood Circulation in Rodents

L Wang, C He, Z Cui, J Liu - 2024 - researchsquare.com
Purpose To evaluate the pharmacological and toxicological safety of TEFAPI-06 in rodents,
offering crucial insights for its clinical trial applications. Methods For bistribution analysis, SD …