The free energy provided by adenosine triphosphate (ATP) hydrolysis is central to many
cellular processes and, therefore, the number of enzymes utilizing ATP as a substrate is …

We report the synthesis and photospectroscopic characterisation of intrinsically fluorescent
triazole-appended cytidines. Fluorescence was found to be highly dependent on solvent …

Many biological systems, especially those based on nucleic acids, are structurally
heterogeneous in solution. We demonstrate here the ability to measure multiple distances …

A or B: RNA–DNA hybrids, key intermediates in gene regulation, were classified by pulsed
electron–electron double resonance (PELDOR) in combination with CD spectroscopy into …

Nowadays, RNA synthesis has become an essential tool not only in the field of molecular
biology and medicine, but also in areas like molecular diagnostics and material sciences …

Biological activity in the cell is predominantly mediated by large multiprotein and protein–
nucleic acid complexes that act together to ensure functional fidelity. Nuclear magnetic …

Recent studies indicate that LRS may act as a leucine sensor for the mTORC1 pathway,
potentially providing an alternative strategy to overcome rapamycin resistance in cancer …

Site-directed spin labeling (SDSL) obtains structural and dynamic information of a
macromolecule using a site-specifically attached stable nitroxide radical. SDSL studies of …

The influence of structural changes of an abasic site in duplex DNA on noncovalent and site-
directed spin labeling (NC-SDSL) of the spin label ç were examined with electron …

PELDOR (pulsed electron–electron double resonance) is an established method to study
intramolecular distances and can give evidence for conformational changes and flexibilities …