Prevention of acute exacerbations of COPD: American college of chest physicians and Canadian thoracic society guideline
GJ Criner, J Bourbeau, RL Diekemper, DR Ouellette… - Chest, 2015 - Elsevier
BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …
New anti-inflammatory targets for chronic obstructive pulmonary disease
PJ Barnes - Nature reviews Drug discovery, 2013 - nature.com
Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation of
the peripheral airways and lung parenchyma, which leads to progressive obstruction of the …
the peripheral airways and lung parenchyma, which leads to progressive obstruction of the …
Glucocorticosteroids: current and future directions
PJ Barnes - British journal of pharmacology, 2011 - Wiley Online Library
Glucocorticoids are the most effective anti‐inflammatory therapy for asthma yet are relatively
ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation …
ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation …
[HTML][HTML] Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation
F Grabcanovic-Musija, A Obermayer, W Stoiber… - Respiratory …, 2015 - Springer
Background COPD is a progressive disease of the airways that is characterized by
neutrophilic inflammation, a condition known to promote the excessive formation of …
neutrophilic inflammation, a condition known to promote the excessive formation of …
Long‐acting muscarinic antagonist (LAMA) plus long‐acting beta‐agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive …
N Horita, A Goto, Y Shibata, E Ota… - Cochrane Database …, 2017 - cochranelibrary.com
Background Three classes of inhaler medications are used to manage chronic obstructive
pulmonary disease (COPD): long‐acting beta‐agonists (LABA), long‐acting muscarinic …
pulmonary disease (COPD): long‐acting beta‐agonists (LABA), long‐acting muscarinic …
[HTML][HTML] PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases
X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …
are critical areas of medical research, as millions of people are affected worldwide. In fact …
[HTML][HTML] Therapeutic role of mesenchymal stem cell-derived exosomes in respiratory disease
MJ Zargar, S Kaviani, M Vasei… - Stem Cell Research & …, 2022 - Springer
Exosomes are extracellular vesicles found in various tissues, blood circulation, and tissue
fluids, secreted into the extracellular environment by fusing a multivesicular body with a …
fluids, secreted into the extracellular environment by fusing a multivesicular body with a …
[HTML][HTML] Guidelines for diagnosis and management of chronic obstructive pulmonary disease: Joint ICS/NCCP (I) recommendations
D Gupta, R Agarwal, AN Aggarwal, VN Maturu… - Lung India, 2013 - journals.lww.com
Chronic obstructive pulmonary disease (COPD) is a major public health problem in India.
Although several International guidelines for diagnosis and management of COPD are …
Although several International guidelines for diagnosis and management of COPD are …
[HTML][HTML] Rational use of inhaled corticosteroids for the treatment of COPD
JK Quint, A Ariel, PJ Barnes - npj Primary Care Respiratory Medicine, 2023 - nature.com
Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …
Inflammation in COPD: implications for management
Chronic obstructive pulmonary disease (COPD) is recognized by the Global Initiative for
Chronic Obstructive Lung Disease guidelines as an inflammatory disease state, and …
Chronic Obstructive Lung Disease guidelines as an inflammatory disease state, and …