Triple inhaled therapy for chronic obstructive pulmonary disease
P Montuschi, M Malerba, G Macis, N Mores… - Drug discovery today, 2016 - Elsevier
Highlights•Triple therapy in a single inhaler is a new therapeutic option for COPD.•Three
fixed dose combinations of inhaled corticosteroids LABA and LAMA are in Phase III of …
fixed dose combinations of inhaled corticosteroids LABA and LAMA are in Phase III of …
Corticosteroid resistance and novel anti-inflammatory therapies in chronic obstructive pulmonary disease: current evidence and future direction
Corticosteroids are widely used in the treatment of chronic obstructive pulmonary disease
(COPD). However, in contrast to their use in mild-to-moderate asthma, they are much less …
(COPD). However, in contrast to their use in mild-to-moderate asthma, they are much less …
Incidence of type II diabetes in chronic obstructive pulmonary disease: a nested case–control study
A Gayle, S Dickinson, C Poole, M Pang… - NPJ Primary Care …, 2019 - nature.com
We investigated the incidence of type II diabetes mellitus (T2DM) among people with COPD
and whether exposure to inhaled corticosteroid (ICS) and exacerbation status was …
and whether exposure to inhaled corticosteroid (ICS) and exacerbation status was …
NMR-based metabolomics for the assessment of inhaled pharmacotherapy in chronic obstructive pulmonary disease patients
The aim of this proof-of-concept, pilot study was the evaluation of the effects of steroid
administration and suspension of an inhaled corticosteroid (ICS)-long-acting β2-agonist …
administration and suspension of an inhaled corticosteroid (ICS)-long-acting β2-agonist …
Macrolide therapy decreases chronic obstructive pulmonary disease exacerbation: a meta-analysis
GY Yao, YL Ma, MQ Zhang, ZC Gao - Respiration, 2013 - karger.com
Background: Macrolide antibiotics have anti-inflammatory effects, and long-term
administration may reduce chronic obstructive pulmonary disease (COPD) exacerbations …
administration may reduce chronic obstructive pulmonary disease (COPD) exacerbations …
A descriptive cohort study of withdrawal from inhaled corticosteroids in COPD patients
S Patel, S Dickinson, K Morris, HF Ashdown… - NPJ Primary Care …, 2022 - nature.com
Inhaled corticosteroid (ICS) therapy is widely prescribed without a history of exacerbations
and consensus guidelines suggest withdrawal of ICS in these patients would reduce the risk …
and consensus guidelines suggest withdrawal of ICS in these patients would reduce the risk …
Recent advances in COPD disease management with fixed-dose long-acting combination therapies
ED Bateman, DA Mahler, CF Vogelmeier… - Expert Review of …, 2014 - Taylor & Francis
Combinations of two long-acting bronchodilators and long-acting bronchodilators with
inhaled corticosteroids (ICS) are recommended therapies in the management of chronic …
inhaled corticosteroids (ICS) are recommended therapies in the management of chronic …
Pulmonary delivery of anti-inflammatory agents
ME Ali, JT McConville, A Lamprecht - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Respiratory infections and diseases are accompanied by or exhibit
inflammation. Recent advances in nanoparticle engineering technology, together with the …
inflammation. Recent advances in nanoparticle engineering technology, together with the …
[HTML][HTML] Inhaled corticosteroids and secondary adrenal insufficiency
V Sannarangappa, R Jalleh - The open respiratory medicine …, 2014 - ncbi.nlm.nih.gov
Inhaled corticosteroids (ICS) have been used as first line treatment of asthma for many
decades. ICS are a form of exogenous glucocorticosteroids that can suppress the …
decades. ICS are a form of exogenous glucocorticosteroids that can suppress the …
慢性阻塞性肺疾病的发病机制和临床药物研究进展
向左娟, 孙宏斌 - 药学与临床研究, 2013 - cqvip.com
慢性阻塞性肺疾病(COPD) 作为一个发病率越来越高的健康杀手, 其发病机制被认为与肺脏因
吸入有害气体或颗粒而引起的异常炎症反应有关. 用于治疗COPD 的药物包括支气管扩张剂和抗 …
吸入有害气体或颗粒而引起的异常炎症反应有关. 用于治疗COPD 的药物包括支气管扩张剂和抗 …