Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Integrative and conjugative elements (ICEs) are widespread mobile DNA that transmit both
vertically, in a host-integrated state, and horizontally, through excision and transfer to new …

Pseudomonas aeruginosa and Staphylococcus aureus are the two most prevalent bacteria
species in the lungs of cystic fibrosis (CF) patients and are associated with poor clinical …

Pseudomonas aeruginosa is a leading cause of chronic respiratory infections in people with
cystic fibrosis (CF), bronchiectasis or chronic obstructive pulmonary disease (COPD), and …

Pseudomonas aeruginosa is one of the main microbial species colonizing the lungs of cystic
fibrosis patients and is responsible for the decline in respiratory function. Despite the hostile …

Antibiotic poly-resistance (multidrug-, extreme-, and pan-drug resistance) is controlled by
adaptive evolution. Darwinian and Lamarckian interpretations of resistance evolution are …

Stenotrophomonas maltophilia has been recognized as an emerging multi-drug resistant
opportunistic pathogen in cystic fibrosis (CF) patients. We report a comparative genomic and …

Cystic fibrosis (CF) is a genetic disorder affecting several organs including airways. Bacterial
infection, inflammation and iron dysbalance play a major role in the chronicity and severity of …

Within-host adaptation is a hallmark of chronic bacterial infections, involving substantial
genomic changes. Recent large-scale genomic data from prolonged infections allow the …

Chronic infection by Pseudomonas aeruginosa in cystic fibrosis (CF) patients is a major
contributor to progressive lung damage and is poorly treated by available antibiotic therapy …