Small vulnerable newborns—big potential for impact
Despite major achievements in child survival, the burden of neonatal mortality has remained
high and even increased in some countries since 1990. Currently, most neonatal deaths are …
high and even increased in some countries since 1990. Currently, most neonatal deaths are …
Diagnosis of neonatal sepsis: the past, present and future
Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …
Epidemiology and immune pathogenesis of viral sepsis
GL Lin, JP McGinley, SB Drysdale… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
Neonatal sepsis: a review of pathophysiology and current management strategies
MA Glaser, LM Hughes, A Jnah… - Advances in neonatal …, 2021 - journals.lww.com
Background: Early-onset sepsis, occurring within 72 hours of birth, and late-onset sepsis,
occurring after this time period, present serious risks for neonates. While culture-based …
occurring after this time period, present serious risks for neonates. While culture-based …
Neonatal sepsis of early onset, and hospital-acquired and community-acquired late onset: a prospective population-based cohort study
E Giannoni, PKA Agyeman, M Stocker… - The Journal of …, 2018 - Elsevier
Objective To assess the epidemiology of blood culture-proven early-(EOS) and late-onset
neonatal sepsis (LOS). Study design All newborn infants admitted to tertiary care neonatal …
neonatal sepsis (LOS). Study design All newborn infants admitted to tertiary care neonatal …
Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low-and middle-income countries
Early development of the microbiome has been shown to affect general health and physical
development of the infant and, although some studies have been undertaken in high-income …
development of the infant and, although some studies have been undertaken in high-income …
Risk factors of neonatal sepsis in India: A systematic review and meta-analysis
Background The incidence of neonatal sepsis in India is the highest in the world. Evidence
regarding its risk factors can guide clinical practice and prevention strategies. Objective To …
regarding its risk factors can guide clinical practice and prevention strategies. Objective To …
Culture-negative early-onset neonatal sepsis—at the crossroad between efficient sepsis care and antimicrobial stewardship
C Klingenberg, RF Kornelisse, G Buonocore… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a leading cause of mortality and morbidity in neonates. Presenting clinical
symptoms are unspecific. Sensitivity and positive predictive value of biomarkers at onset of …
symptoms are unspecific. Sensitivity and positive predictive value of biomarkers at onset of …
[PDF][PDF] Neonatal sepsis
IO Odabasi, A Bulbul - Şişli Etfal Hastanesi Tip Bülteni, 2020 - jag.journalagent.com
Neonatal sepsis is associated with severe morbidity and mortality in the neonatal period.
Clinical manifestations range from subclinical infection to severe local or systemic infection …
Clinical manifestations range from subclinical infection to severe local or systemic infection …
A neonatal sequential organ failure assessment score predicts mortality to late-onset sepsis in preterm very low birth weight infants
JL Wynn, RA Polin - Pediatric research, 2020 - nature.com
Background An operational definition of organ dysfunction applicable to neonates that
predicts mortality in the setting of infection is lacking. We determined the utility of an …
predicts mortality in the setting of infection is lacking. We determined the utility of an …