[HTML][HTML] The fundamental role of miR-10b in metastatic cancer

P Sheedy, Z Medarova - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Small, non-coding strands of RNA have been identified as a significant player in the
pathology of cancer. One of the first miRNAs to be shown as having aberrant expression in …

[HTML][HTML] Epigenetic regulation and cancer

QW Chen, XY Zhu, YY Li, ZQ Meng - Oncology reports, 2014 - spandidos-publications.com
Abstract 'Epigenetics' is defined as the inheritable changes in gene expression with no
alterations in DNA sequences. Epigenetics is a rapidly expanding field, and the study of …

[HTML][HTML] Small in size, but large in action: microRNAs as potential modulators of PTEN in breast and lung cancers

AJ Abadi, A Zarrabi, MH Gholami, S Mirzaei… - Biomolecules, 2021 - mdpi.com
MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …

[HTML][HTML] The curcumin analog EF24 targets NF-κB and miRNA-21, and has potent anticancer activity in vitro and in vivo

CH Yang, J Yue, M Sims, LM Pfeffer - PloS one, 2013 - journals.plos.org
EF24 is a curcumin analog that has improved anticancer activity over curcumin, but its
therapeutic potential and mechanism of action is unknown, which is important to address as …

microRNAs in breast cancer development and treatment

D Serpico, L Molino, S Di Cosimo - Cancer treatment reviews, 2014 - Elsevier
Abstract microRNAs (herein after miRNAs) represent a recently uncovered class of small
and endogenous non-coding RNAs. miRNAs play a well conserved and crucial role in …

[HTML][HTML] Clinical significance of serum miR-21 in breast cancer compared with CA153 and CEA

J Gao, Q Zhang, J Xu, L Guo, X Li - Chinese journal of cancer …, 2013 - ncbi.nlm.nih.gov
Objective MicroRNA-21 (miR-21) has been shown to be a key regulator of carcinogenesis.
There were few reports about the comparison of serum miR-21 with conventional tumor …

miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF-1 expression

CC Mandal, T Ghosh-Choudhury, N Dey… - …, 2012 - academic.oup.com
Increasing evidence shows the beneficial effects of fish oil on breast cancer growth and
invasion in vitro and in animal models. Expression of CSF-1 (colony stimulating factor-1) by …

[HTML][HTML] Pregnancy-associated breast cancer: a diagnostic and therapeutic challenge

F Galati, V Magri, PA Arias-Cadena, G Moffa, V Rizzo… - Diagnostics, 2023 - mdpi.com
Pregnancy-associated breast cancer (PABC) is commonly defined as a breast cancer
occurring during pregnancy, throughout 1 year postpartum, or during lactation. Despite …

Breast cancer and microRNAs: therapeutic impact

MV Iorio, P Casalini, C Piovan, L Braccioli, E Tagliabue - The Breast, 2011 - Elsevier
Despite advances in detection and therapies, breast cancer is still the leading cause of
cancer death in women worldwide. The etiology of this neoplasm is complex, and both …

HTLV-1 bZIP factor HBZ promotes cell proliferation and genetic instability by activating OncomiRs

C Vernin, M Thenoz, C Pinatel, A Gessain, O Gout… - Cancer research, 2014 - AACR
Viruses disrupt the host cell microRNA (miRNA) network to facilitate their replication. Human
T-cell leukemia virus type I (HTLV-1) replication relies on the clonal expansion of its host …